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Western Blot (WB) (Western Blot (WB) analysis of HAPLN4 polyclonal antibody at 1:500 dilutionLane1:The thymus tissue lysate of Mouse (30ug) Lane2:The thymus tissue lysate of Rat (30ug) Lane3:The peripheral blood tissue lysate of Mouse (30ug) Lane4:The peripheral blood tissue lysate of Rat (30ug) ))

Rabbit HAPLN4 Polyclonal Antibody | anti-HAPLN4 antibody

HAPLN4 Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
HAPLN4; Polyclonal Antibody; HAPLN4 Polyclonal Antibody; Hyaluronan and proteoglycan link protein 4; Brain link protein 2; BRAL2; KIAA1926; anti-HAPLN4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
HAPLN4 polyclonal antibody detects endogenous levels of HAPLN4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
402
Applicable Applications for anti-HAPLN4 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding toamino acids 114-159 Human HAPLN4.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of HAPLN4 polyclonal antibody at 1:500 dilutionLane1:The thymus tissue lysate of Mouse (30ug) Lane2:The thymus tissue lysate of Rat (30ug) Lane3:The peripheral blood tissue lysate of Mouse (30ug) Lane4:The peripheral blood tissue lysate of Rat (30ug) ))

Western Blot (WB) (Western Blot (WB) analysis of HAPLN4 polyclonal antibody at 1:500 dilutionLane1:The thymus tissue lysate of Mouse (30ug) Lane2:The thymus tissue lysate of Rat (30ug) Lane3:The peripheral blood tissue lysate of Mouse (30ug) Lane4:The peripheral blood tissue lysate of Rat (30ug) ))
Related Product Information for anti-HAPLN4 antibody
HAPLN4 (Hyaluronan and proteoglycan link protein 4) is a 360 amino acid protein encoded by the human gene HAPLN4. HAPLN4 belongs to the HAPLN family and contains 1 Ig-like C2-type (immunoglobulin-like) domain and two Link domains. HAPLN4 mediates the binding of complexes containing hyaluronic acid. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN4 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN4 may also be involved in the formation of extracellular matrices contributing to perineuronal nets and facilitate the understanding of a functional role of these extracellular matrices. HAPLN4 is widely expressed with highest levels in spleen and placenta.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 42kDa
NCBI Official Full Name
hyaluronan and proteoglycan link protein 4
UniProt Protein Name
Hyaluronan and proteoglycan link protein 4
UniProt Gene Name
HAPLN4
UniProt Synonym Gene Names
BRAL2; KIAA1926
UniProt Entry Name
HPLN4_HUMAN

Uniprot Description

HAPLN4: Binds to hyaluronic acid and may be involved in formation of the extracellular matrix. Belongs to the HAPLN family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: proteinaceous extracellular matrix

Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding

Biological Process: central nervous system development; cell adhesion; skeletal development

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Product Notes

The HAPLN4 hapln4 (Catalog #AAA3007399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HAPLN4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HAPLN4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the HAPLN4 hapln4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAPLN4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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