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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using GUCY1A3 Polyclonal Antibody at dilution 1:40)

Rabbit GUCY1A3 Polyclonal Antibody | anti-GUCY1A3 antibody

GUCY1A3 Polyclonal Antibody

Gene Names
GUCY1A3; GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
GUCY1A3; Polyclonal Antibody; GUCY1A3 Polyclonal Antibody; GUCA3; GC-SA3; GUC1A3; GUCSA3; GUCY1A1; anti-GUCY1A3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.5mg/mL (varies by lot)
Sequence Length
690
Applicable Applications for anti-GUCY1A3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human GUCY1A3
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using GUCY1A3 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using GUCY1A3 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using GUCY1A3 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using GUCY1A3 Polyclonal Antibody at dilution 1:40)
Related Product Information for anti-GUCY1A3 antibody
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3', 5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,184 Da
NCBI Official Full Name
guanylate cyclase soluble subunit alpha-3 isoform A
NCBI Official Synonym Full Names
guanylate cyclase 1, soluble, alpha 3
NCBI Official Symbol
GUCY1A3
NCBI Official Synonym Symbols
GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A1
NCBI Protein Information
guanylate cyclase soluble subunit alpha-3; GC-S-alpha-1; GCS-alpha-3; soluble guanylate cyclase large subunit
UniProt Protein Name
Guanylate cyclase soluble subunit alpha-3
Protein Family
UniProt Gene Name
GUCY1A3
UniProt Synonym Gene Names
GUC1A3; GUCSA3; GUCY1A1; GCS-alpha-3
UniProt Entry Name
GCYA3_HUMAN

NCBI Description

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Protein type: Lyase; Guanylyl cyclase; EC 4.6.1.2; Receptor, misc.; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 4q31.1-q31.2

Cellular Component: guanylate cyclase complex, soluble

Molecular Function: guanylate cyclase activity; GTP binding; heme binding; receptor activity

Biological Process: cGMP biosynthetic process; relaxation of vascular smooth muscle; positive regulation of cGMP biosynthetic process; blood circulation; regulation of blood pressure; blood coagulation; response to defense-related host nitric oxide production; nitric oxide mediated signal transduction

Disease: Moyamoya Disease 6 With Achalasia

Research Articles on GUCY1A3

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Product Notes

The GUCY1A3 gucy1a3 (Catalog #AAA2520521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GUCY1A3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GUCY1A3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the GUCY1A3 gucy1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GUCY1A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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