Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit GUCY1A1 / GUCY1A3 Polyclonal Antibody | anti-GUCY1A1 / GUCY1A3 antibody
Anti-GUCY1A1 / GUCY1A3 Antibody (aa374-423) IHC-plus
IHC-P (5 ug/ml)
WB (1:500 - 1:1000)
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot analysis of lysate from A549 cells, using GCS-a-1 antibody.)
Western Blot (WB)
(Western blot analysis of lysate from A549 cells, using GCS-a-1 antibody.)
NCBI and Uniprot Product Information
NCBI Description
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Protein type: Nucleotide Metabolism - purine; Receptor, misc.; EC 4.6.1.2; Lyase; Guanylyl cyclase
Chromosomal Location of Human Ortholog: 4q31.1-q31.2
Cellular Component: guanylate cyclase complex, soluble; plasma membrane
Molecular Function: adenylate cyclase activity; GTP binding; guanylate cyclase activity; heme binding; protein binding; protein heterodimerization activity; receptor activity
Biological Process: blood circulation; blood coagulation; cGMP biosynthetic process; nitric oxide mediated signal transduction; positive regulation of cGMP biosynthetic process; regulation of blood pressure; relaxation of vascular smooth muscle; response to defense-related host nitric oxide production; response to herbicide; response to organic cyclic substance
Disease: Moyamoya Disease 6 With Achalasia
Research Articles on GUCY1A1 / GUCY1A3
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Product Notes
The GUCY1A1 / GUCY1A3 gucy1a3 (Catalog #AAA2400467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GUCY1A1 / GUCY1A3 Antibody (aa374-423) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's GUCY1A1 / GUCY1A3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:10000) IHC-P (5 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the GUCY1A1 / GUCY1A3 gucy1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GUCY1A1 / GUCY1A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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