Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is blocked with the synthesized peptide.)
Rabbit Guanylate Cyclase beta Polyclonal Antibody | anti-GCYB1 antibody
Guanylate Cyclase beta Antibody
Gene Names
GUCY1B1; GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B3; GC-S-beta-1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
Guanylate Cyclase beta; Polyclonal Antibody; Guanylate Cyclase beta Antibody; GCS-beta-1; GCS-beta-3; guanylate cyclase soluble subunit beta-1; GUCY1B1; soluble guanylate cyclase small subunit; anti-GCYB1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Guanylate Cyclase beta Antibody detects endogenous levels of total Guanylate Cyclase beta protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
599
Applicable Applications for anti-GCYB1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:5000
IHC: 1:50~1:100
ELISA: 1:5000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human Guanylate Cyclase beta.
Immunogen Range
Oct-59
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is blocked with the synthesized peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Guanylate Cyclase beta Antibody. The picture on the right is blocked with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of lysates from HUVEC cells, using Guanylate Cyclase beta Antibody. The lane on the right is blocked with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of lysates from HUVEC cells, using Guanylate Cyclase beta Antibody. The lane on the right is blocked with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70 kDa
NCBI Official Full Name
guanylate cyclase soluble subunit beta-1 isoform 2
NCBI Official Synonym Full Names
guanylate cyclase 1 soluble subunit beta 1
NCBI Official Symbol
GUCY1B1
NCBI Official Synonym Symbols
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B3; GC-S-beta-1
NCBI Protein Information
guanylate cyclase soluble subunit beta-1
UniProt Protein Name
Guanylate cyclase soluble subunit beta-1
UniProt Gene Name
GUCY1B3
UniProt Synonym Gene Names
GUC1B3; GUCSB3; GUCY1B1; GCS-beta-3
NCBI Description
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Uniprot Description
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Research Articles on GCYB1
Similar Products
Product Notes
The GCYB1 gucy1b3 (Catalog #AAA9504622) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Guanylate Cyclase beta Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Guanylate Cyclase beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000. Researchers should empirically determine the suitability of the GCYB1 gucy1b3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Guanylate Cyclase beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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