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Western Blot (WB) (Western blot analysis of GTPBP4 using COLO205 whole lysates.)

Rabbit anti-Human GTPBP4 Polyclonal Antibody | anti-GTPBP4 antibody

GTPBP4 Antibody

Gene Names
GTPBP4; NGB; CRFG; NOG1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
GTPBP4; Polyclonal Antibody; GTPBP4 Antibody; Chronic renal failure gene protein; CRFG; G protein binding protein CRFG; GTP binding protein 4; GTP-binding protein NGB; Gtpbp4; NGB; NOG1; NOG1_HUMAN; Nucleolar GTP binding protein 1; Nucleolar GTP-binding protein 1; anti-GTPBP4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
GTPBP4 antibody detects endogenous levels of total GTPBP4
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
634
Applicable Applications for anti-GTPBP4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human GTPBP4
Subcellular Location
Nucleus > Nucleolus.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Dog, Chicken
Similarity
Pig (100%), Bovine (90%), Horse (100%), Sheep (90%), Dog (100%), Chicken (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of GTPBP4 using COLO205 whole lysates.)

Western Blot (WB) (Western blot analysis of GTPBP4 using COLO205 whole lysates.)
Related Product Information for anti-GTPBP4 antibody
Function: Involved in the biogenesis of the 60S ribosomal subunit.
Similarity: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 74 kDa
Predicted: 74 kDa
NCBI Official Full Name
nucleolar GTP-binding protein 1
NCBI Official Synonym Full Names
GTP binding protein 4
NCBI Official Symbol
GTPBP4
NCBI Official Synonym Symbols
NGB; CRFG; NOG1
NCBI Protein Information
nucleolar GTP-binding protein 1
UniProt Protein Name
Nucleolar GTP-binding protein 1
UniProt Gene Name
GTPBP4
UniProt Synonym Gene Names
CRFG; NOG1

NCBI Description

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in the biogenesis of the 60S ribosomal subunit.

Research Articles on GTPBP4

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Product Notes

The GTPBP4 gtpbp4 (Catalog #AAA9608413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GTPBP4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GTPBP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the GTPBP4 gtpbp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTPBP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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