Goat GTF3C4 Polyclonal Antibody | anti-GTF3C4 antibody
Goat anti-GTF3C4 Antibody
Gene Names
GTF3C4; KAT12; TFIII90; TFIIIC90; TFIIIC290; TF3C-delta; TFIIICDELTA
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
GTF3C4; Polyclonal Antibody; Goat anti-GTF3C4 Antibody; general transcription factor IIIC; polypeptide 4; 90kDa; FLJ21002; KAT12; MGC138450; TFIII90; TFIIIC90; TFIIICdelta; TFiiiC2-90; OTTHUMP00000022434; polypeptide 4 (90kD); GTF3C4 antibody; 90kDa antibody; FLJ21002 antibody; KAT12 antibody; MGC138450 antibody; TFIII90 antibody; TFIIIC90 antibody; TFIIICdelta antibody; TFiiiC2-90 antibody; OTTHUMP00000022434 antibody; polypeptide 4 (90kD) antibody; anti-GTF3C4 antibody
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
ERLYETSYRLSKNE
Sequence Length
822
Applicable Applications for anti-GTF3C4 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Preliminary experiments gave an approx 80kDa band in lysates of cell line K562 after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 92. 0kDa according to NP_036336.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide.
Western Blot: Preliminary experiments gave an approx 80kDa band in lysates of cell line K562 after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 92. 0kDa according to NP_036336.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence C-ERLYETSYRLSKNE, from the internal region of the protein sequence according to NP_036336.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,982 Da
NCBI Official Full Name
general transcription factor 3C polypeptide 4
NCBI Official Synonym Full Names
general transcription factor IIIC subunit 4
NCBI Official Symbol
GTF3C4
NCBI Official Synonym Symbols
KAT12; TFIII90; TFIIIC90; TFIIIC290; TF3C-delta; TFIIICDELTA
NCBI Protein Information
general transcription factor 3C polypeptide 4
UniProt Protein Name
General transcription factor 3C polypeptide 4
Protein Family
UniProt Gene Name
GTF3C4
UniProt Synonym Gene Names
TFIIIC 90 kDa subunit; TFIIIC90
UniProt Entry Name
TF3C4_HUMAN
Uniprot Description
GTF3C4: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. Belongs to the TFIIIC subunit 4 family.
Protein type: EC 2.3.1.48; Acetyltransferase
Chromosomal Location of Human Ortholog: 9q34.13
Cellular Component: nucleoplasm; transcription factor TFIIIC complex
Molecular Function: DNA binding; enzyme activator activity; histone acetyltransferase activity; protein binding
Biological Process: 5S class rRNA transcription; histone acetylation; positive regulation of catalytic activity; transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase III promoter; transcription, DNA-dependent; tRNA transcription from RNA polymerase III promoter
Research Articles on GTF3C4
1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
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Product Notes
The GTF3C4 gtf3c4 (Catalog #AAA422243) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-GTF3C4 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's GTF3C4 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Preliminary experiments gave an approx 80kDa band in lysates of cell line K562 after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 92. 0kDa according to NP_036336.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the GTF3C4 gtf3c4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ERLYETSYRL SKNE. It is sometimes possible for the material contained within the vial of "GTF3C4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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