Rabbit anti-Human, Rat GTF3C4 Polyclonal Antibody | anti-GTF3C4 antibody

GTF3C4 Polyclonal Antibody

Cat. Num. AAA9434528

• Gene Names: GTF3C4; KAT12; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA
• Reactivity: Human, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity purification
• Synonyms: GTF3C4; Polyclonal Antibody; GTF3C4 Polyclonal Antibody; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA; general transcription factor IIIC subunit 4; anti-GTF3C4 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 50% glycerol, pH7.4

• Applicable Applications for anti-GTF3C4 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
• Immunogen: Recombinant fusion protein of human GTF3C4 (NP_036336.2).
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using GTF3C4 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of C6 cells using GTF3C4 Polyclonal Antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U-2 OS cells using GTF3C4 Polyclonal Antibody.)

Product Categories/Family for anti-GTF3C4 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 156119605
• NCBI GeneID: 9329
• NCBI Accession #: NP_036336.2
• NCBI GenBank Nucleotide #: NM_012204.2
• UniProt Accession #: Q9UKN8; Q5VZJ7
• Molecular Weight: 91,982 Da
• NCBI Official Full Name: general transcription factor 3C polypeptide 4
• NCBI Official Synonym Full Names: general transcription factor IIIC, polypeptide 4, 90kDa
• NCBI Official Symbol: GTF3C4
• NCBI Official Synonym Symbols: KAT12; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA
• NCBI Protein Information: general transcription factor 3C polypeptide 4; TF3C-delta; TFIIIC 90 kDa subunit; general transcription factor 3C 4; transcription factor IIIC subunit delta; transcription factor IIIC 90 kDa subunit
• UniProt Protein Name: General transcription factor 3C polypeptide 4
• Protein Family: General transcription factor 3C polypeptide
• UniProt Gene Name: GTF3C4
• UniProt Synonym Gene Names: TFIIIC 90 kDa subunit; TFIIIC90
• UniProt Entry Name: TF3C4_HUMAN

Uniprot Description

GTF3C4: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. Belongs to the TFIIIC subunit 4 family.

Protein type: EC 2.3.1.48; Acetyltransferase

Chromosomal Location of Human Ortholog: 9q34.13

Cellular Component: nucleoplasm; transcription factor TFIIIC complex

Molecular Function: protein binding; histone acetyltransferase activity; DNA binding; enzyme activator activity

Biological Process: transcription from RNA polymerase III promoter; positive regulation of catalytic activity; transcription initiation from RNA polymerase III promoter; transcription, DNA-dependent; 5S class rRNA transcription; gene expression; histone acetylation; tRNA transcription from RNA polymerase III promoter