Rabbit Gsh1 Polyclonal Antibody | anti-Gsh1 antibody

Gsh1 Polyclonal Antibody

Cat. Num. AAA3015232

• Gene Names: GSX1; GSH1; Gsh-1
• Reactivity: Human, Mouse, Rat, Dog, Pig, Sheep
• Applications: Western Blot
• Purity: affinity purified by Protein A
• Synonyms: Gsh1; Polyclonal Antibody; Gsh1 Polyclonal Antibody; GS homeo box protein 1; GS homeobox 1; GSH1; GSX1; GSX1_HUMAN; Homeobox protein GSH-1 ; Homeobox protein Gsh1; anti-Gsh1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Dog, Pig, Sheep
• Clonality: Polyclonal
• Specificity: Gsh1 Polyclonal Antibody detects endogenous levels of Gsh1 protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-Gsh1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-2000
• Immunogen: KLH conjugated synthetic peptide derived from human Gsh1
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

Related Product Information for anti-Gsh1 antibody

Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.

NCBI and Uniprot Product Information

• NCBI GI #: 33457326
• NCBI GeneID: 219409
• NCBI Accession #: NP_663632.1
• NCBI GenBank Nucleotide #: NM_145657.2
• UniProt Accession #: Q9H4S2; Q9UD62
• Molecular Weight: 27,883 Da
• NCBI Official Full Name: GS homeobox 1
• NCBI Official Synonym Full Names: GS homeobox 1
• NCBI Official Symbol: GSX1
• NCBI Official Synonym Symbols: GSH1; Gsh-1
• NCBI Protein Information: GS homeobox 1
• UniProt Protein Name: GS homeobox 1
• UniProt Gene Name: GSX1
• UniProt Synonym Gene Names: GSH1

Uniprot Description

Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development.