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Sheep anti-Rat Growth Hormone-Releasing Hormone Polyclonal Antibody | anti-LOC100134850 antibody

Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody

Reactivity
Rat
Applications
Immunohistochemistry, immunoassay, Radioimmunoassay
Synonyms
Growth Hormone-Releasing Hormone; Polyclonal Antibody; Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody; GHRH; Somatocrinin; Somatoliberin; GH-RH; Growth hormone-releasing factor (GHRF orGRF); Somatotropin-releasing hormone (SRH); Somatotropin-releasing factor (SRF); Somatorelin; anti-LOC100134850 antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody recognizes the rat GHRH and it shows no cross-reactivity with SRIF-14, SRIF-28 rGH, LH, FSH, PRL calcitonin, insulin, glucagon ovine CRF, secretin, vasoactive intestinal peptide, and cholecystokinin-8
Form/Format
Lyophilized Serum
Sequence Length
174
Applicable Applications for anti-LOC100134850 antibody
Immunohistochemistry (IHC), Radioimmunoassay (RIA), In vivo Passive Immunization
Application Notes
If reconstituted in 50 muL: IHC: 1:15000; In vivo Passive Immunization: neat serum; RIA: In a RIA for rGRF-(1043), at a final dilution of 1:785,000, this antiserum binds 35% of [125l]-rGRF and can detect 7mug/assay tube.
Immunogen
synthetic rat GHRH (1-29)NH2
Preservative
None
Preparation and Storage
Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-LOC100134850 antibody
GHRH belongs to the glucagon family produced in the hypothalamus. It is essential for normal linear growth and has important metabolic effects throughout life. GHRH stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. GHRH is released from neurosecretory nerve terminals of arcuate neurons, and is carried by the hypothalamo-hypophyseal portal system to the anterior pituitary gland, where it stimulates growth hormone(GH) secretion by stimulating the growth hormone-releasing hormone receptor.
References
1. Stroh T-Subcellular dynamics of somatostatin receptor subtype 1 in the rat arcuate nucleus: receptor localization and synaptic connectivity vary in paralle. 2. Tannenbaum GS-Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone. 3. Tannenbaum GS-Cysteamine-induced enhancement of growth hormonereleasing factor (GRF) immunoreactivity in arcuate neurons: morphological evidence for putative. 4. Tannenbaum GS-Mechanisms of impaired growth hormone secretion in genetically obese Zucker rats: roles of growth hormone-releasing factor and somatostatin.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
GHRH/PACAP
NCBI Official Symbol
LOC100134850
NCBI Protein Information
GHRH/PACAP precursor

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Product Notes

The LOC100134850 (Catalog #AAA588353) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Growth Hormone-Releasing Hormone can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Radioimmunoassay (RIA), In vivo Passive Immunization. If reconstituted in 50 muL: IHC: 1:15000; In vivo Passive Immunization: neat serum; RIA: In a RIA for rGRF-(1043), at a final dilution of 1:785,000, this antiserum binds 35% of [125l]-rGRF and can detect 7mug/assay tube. Researchers should empirically determine the suitability of the LOC100134850 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Growth Hormone-Releasing Hormone, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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