Goat GRIN2D Polyclonal Antibody | anti-GRIN2D antibody
Goat anti-GRIN2D Antibody
Western Blot: Preliminary experiments gave an approx 80kDa band in Human Brain (Cerebellum) and in Mouse Brain and Rat Brain lysates after 0. 02ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 144kDa according to NP_000827.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI and Uniprot Product Information
NCBI Description
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
Uniprot Description
NMDAR2D: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.
Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: cell junction; intracellular; N-methyl-D-aspartate selective glutamate receptor complex; plasma membrane; postsynaptic membrane
Molecular Function: extracellular-glutamate-gated ion channel activity; N-methyl-D-aspartate selective glutamate receptor activity; protein binding; Ras guanyl-nucleotide exchange factor activity
Biological Process: adult locomotory behavior; ionotropic glutamate receptor signaling pathway; MAPKKK cascade; positive regulation of GTPase activity; regulation of sensory perception of pain; signal transduction; startle response; synaptic transmission
Research Articles on GRIN2D
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Product Notes
The GRIN2D grin2d (Catalog #AAA421593) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-GRIN2D Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GRIN2D can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave an approx 80kDa band in Human Brain (Cerebellum) and in Mouse Brain and Rat Brain lysates after 0. 02ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 144kDa according to NP_000827.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the GRIN2D grin2d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TRRGSAHFSS LESE. It is sometimes possible for the material contained within the vial of "GRIN2D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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