Western Blot (WB)
(Western blot analysis of Granulin expression in HepG2 (A), MCF7 (B), mouse liver (C), mouse kidney (D) whole cell lysates.)
Rabbit anti-Human, Mouse Granulin Polyclonal Antibody | anti-GRN antibody
Anti-Granulin Antibody
Western Blot (WB)
(Western blot analysis of Granulin expression in HepG2 (A), MCF7 (B), mouse liver (C), mouse kidney (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Granulin expression in HepG2 (A), MCF7 (B), mouse liver (C), mouse kidney (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
Research Articles on GRN
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Product Notes
The GRN grn (Catalog #AAA8292224) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Granulin Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Granulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1/500 - 1/2000. Researchers should empirically determine the suitability of the GRN grn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Granulin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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