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Typical Testing Data/Standard Curve (for reference only)

Human Granulin (GRN) ELISA Kit | GRN elisa kit

Human Granulin (GRN) ELISA Kit

Gene Names
GRN; GEP; GP88; PEPI; PGRN; CLN11; PCDGF
Reactivity
Human
Synonyms
Granulin (GRN); Human Granulin (GRN) ELISA Kit; GEP GP88 PCDGF PEPI PGRN Proepithelin Acrogranin Glycoprotein of 88 Kda Paragranulin; GRN elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
593
Samples
Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Assay Type
Sandwich
Detection Range
1.56-100ng/mL
Sensitivity
0.62ng/mL
Intra Assay
CV<10%
Inter Assay
CV<12%
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44,132 Da
NCBI Official Full Name
granulins
NCBI Official Synonym Full Names
granulin precursor
NCBI Official Symbol
GRN
NCBI Official Synonym Symbols
GEP; GP88; PEPI; PGRN; CLN11; PCDGF
NCBI Protein Information
granulins
UniProt Protein Name
Granulins
Protein Family
UniProt Gene Name
GRN
UniProt Synonym Gene Names
PEPI; GP88; Glycoprotein 88

NCBI Description

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.

Research Articles on GRN

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Product Notes

The Human GRN grn (Catalog #AAA451096) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA451096 ELISA Kit recognizes Human GRN. It is sometimes possible for the material contained within the vial of "Granulin (GRN), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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