Rabbit anti-Human, Mouse GPRASP1 Polyclonal Antibody | anti-GPRASP1 antibody

GPRASP1-Specific Rabbit Polyclonal

Cat. Num. AAA769844

• Gene Names: GPRASP1; GASP; GASP1; GASP-1
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: GPRASP1; Polyclonal Antibody; GPRASP1-Specific Rabbit Polyclonal; anti-GPRASP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1395

• Applicable Applications for anti-GPRASP1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: G protein-coupled receptor associated sorting protein 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain using MBS769844 (GPRASP1-Specific antibody) at dilution of 1:100)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS769844 (GPRASP1-Specific antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 150378528
• NCBI GeneID: 9737
• NCBI Accession #: NP_001092881.1
• NCBI GenBank Nucleotide #: NM_001099411.1
• Molecular Weight: 156,865 Da
• NCBI Official Full Name: G-protein coupled receptor-associated sorting protein 1
• NCBI Official Synonym Full Names: G protein-coupled receptor associated sorting protein 1
• NCBI Official Symbol: GPRASP1
• NCBI Official Synonym Symbols: GASP; GASP1; GASP-1
• NCBI Protein Information: G-protein coupled receptor-associated sorting protein 1
• UniProt Protein Name: G-protein coupled receptor-associated sorting protein 1
• Protein Family: G-protein coupled receptor-associated sorting protein
• UniProt Gene Name: GPRASP1
• UniProt Synonym Gene Names: GASP; KIAA0443; GASP-1
• UniProt Entry Name: GASP1_HUMAN

NCBI Description

This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]

Uniprot Description

GPRASP1: May modulate lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes. Belongs to the GPRASP family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: endosome to lysosome transport