Rabbit anti-Human GPR81 Polyclonal Antibody | anti-GPR81 antibody
GPR81 antibody
Gene Names
HCAR1; HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR
Reactivity
Human
Applications
Immunohistochemistry
Purity
GPR81 antibody was purified by affinity chromatography.
Synonyms
GPR81; Polyclonal Antibody; GPR81 antibody; Polyclonal GPR81; Anti-GPR81; GPR -81; GPR 81; FKSG80; anti-GPR81 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human
Purity/Purification
GPR81 antibody was purified by affinity chromatography.
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
346
Applicable Applications for anti-GPR81 antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 11 ug/ml
Biological Significance
G protein-coupled receptors (GPCRs), comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. G protein-coupled receptors are found only in eukaryotes, including yeast, choanoflagellates, and animals. Lactate activates the GPR81 receptor which in turn inhibits lipolysis in fat cells.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
GPR81 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-GPR81 antibody
Rabbit polyclonal GPR81 antibody
Product Categories/Family for anti-GPR81 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,295 Da
NCBI Official Full Name
hydroxycarboxylic acid receptor 1
NCBI Official Synonym Full Names
hydroxycarboxylic acid receptor 1
NCBI Official Symbol
HCAR1
NCBI Official Synonym Symbols
HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR
NCBI Protein Information
hydroxycarboxylic acid receptor 1
UniProt Protein Name
Hydroxycarboxylic acid receptor 1
UniProt Gene Name
HCAR1
UniProt Synonym Gene Names
GPR104; GPR81; HCA1
UniProt Entry Name
HCAR1_HUMAN
NCBI Description
G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Feb 2005]
Uniprot Description
Gpr81: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; response to estradiol stimulus
Research Articles on GPR81
Similar Products
Product Notes
The GPR81 hcar1 (Catalog #AAA535508) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPR81 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPR81 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 11 ug/ml. Researchers should empirically determine the suitability of the GPR81 hcar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR81, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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