Western Blot (WB)
(Western blot analysis of GPR64 expression in A431 whole cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit GPR64 Polyclonal Antibody | anti-GPR64 antibody
GPR64 Antibody
Gene Names
ADGRG2; HE6; EDDM6; GPR64; CBAVDX; TM7LN2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
GPR64; Polyclonal Antibody; GPR64 Antibody; Epididymis specific protein 6; FLJ00282; G protein coupled receptor 64; G protein coupled receptor epididymis specific; GPR 64; HE 6; He 6 receptor; HE6; He6 receptor; MGC104454; MGC138738; MGC138739; TM7LN2; anti-GPR64 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GPR64 antibody detects endogenous levels of total GPR64
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1017
Applicable Applications for anti-GPR64 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Cell Membrane; Multipass Membrane Protein.
Tissue Specificity
Epididymis-specific expression (at protein level). Both subunits are associated with apical membranes of efferent ductule and proximal epididymal duct epithelia. Mainly expressed in the nonciliated principal cells of the proximal excurrent ducts. Specifically over-expressed in Ewing sarcomas but also up-regulated in a number of carcinomas derived from prostate, kidney or lung.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (92%), Bovine (92%), Horse (92%), Sheep (92%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of GPR64 expression in A431 whole cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of GPR64 expression in A431 whole cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-GPR64 antibody
Function: Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.
Subunit Structure: Heterodimer of 2 chains generated by proteolytic processing; the large extracellular N-terminal fragment and the membrane-bound C-terminal fragment predominantly remain associated and non-covalently linked.
Post-translational Modifications: Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. Highly glycosylated.
Similarity: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Subunit Structure: Heterodimer of 2 chains generated by proteolytic processing; the large extracellular N-terminal fragment and the membrane-bound C-terminal fragment predominantly remain associated and non-covalently linked.
Post-translational Modifications: Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. Highly glycosylated.
Similarity: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 112 kDa
Predicted: 112 kDa
Predicted: 112 kDa
NCBI Official Full Name
adhesion G-protein coupled receptor G2 isoform 1
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor G2
NCBI Official Symbol
ADGRG2
NCBI Official Synonym Symbols
HE6; EDDM6; GPR64; CBAVDX; TM7LN2
NCBI Protein Information
adhesion G-protein coupled receptor G2
UniProt Protein Name
Adhesion G-protein coupled receptor G2
UniProt Gene Name
ADGRG2
UniProt Synonym Gene Names
He6
NCBI Description
This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.
Research Articles on GPR64
Similar Products
Product Notes
The GPR64 adgrg2 (Catalog #AAA9604272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPR64 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPR64 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GPR64 adgrg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR64, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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