Testing Data
(Gel: 10%SDS-PAGE Lysate: 40 ug Human small intestine stromal tumors tissue lysate Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds)
Rabbit GPR6 Polyclonal Antibody | anti-GPR6 antibody
GPR6 Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
GPR6; Polyclonal Antibody; GPR6 Antibody; G protein-coupled receptor 7; anti-GPR6 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total GPR6 protein.
Form/Format
Supplied at 0.4mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
362
Applicable Applications for anti-GPR6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
Immunogen Type
Peptide-KLH
Immunogen Description
Synthetic peptide corresponding to a region derived from 347-362 amino acids of Human G protein-coupled receptor 7
Target Name
GPR6
Preparation and Storage
Store at -20 degree C/1 year
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40 ug Human small intestine stromal tumors tissue lysate Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds)
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40 ug Human small intestine stromal tumors tissue lysate Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 31210 (GPR6 Antibody) at dilution 1/10, on the right is treated with the synthetic peptide.)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 31210 (GPR6 Antibody) at dilution 1/10, on the right is treated with the synthetic peptide.)
Related Product Information for anti-GPR6 antibody
G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6gene. GPR6 is a member of the G protein-coupled receptor family of transmembrane receptors. It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate. GPR6 up-regulates cyclic AMP levels and promotes neurite outgrowth.
Product Categories/Family for anti-GPR6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,439 Da
NCBI Official Full Name
G-protein coupled receptor 6 isoform b
NCBI Official Synonym Full Names
G protein-coupled receptor 6
NCBI Official Symbol
GPR6
NCBI Protein Information
G-protein coupled receptor 6
UniProt Protein Name
G-protein coupled receptor 6
Protein Family
UniProt Gene Name
GPR6
UniProt Entry Name
GPR6_HUMAN
Uniprot Description
GPR6: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: integral to plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration
Research Articles on GPR6
Similar Products
Product Notes
The GPR6 gpr6 (Catalog #AAA9406111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPR6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GPR6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the GPR6 gpr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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