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Testing Data (Gel: 10%SDS-PAGE Lysate: 40 ug Human liver cancer tissue lysate Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds)

Rabbit anti-Human SCTR Polyclonal Antibody | anti-SCTR antibody

SCTR Antibody

Gene Names
SCTR; SR
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
SCTR; Polyclonal Antibody; SCTR Antibody; secretin receptor; SR; anti-SCTR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total SCTR protein.
Form/Format
Supplied at 1.2mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
440
Applicable Applications for anti-SCTR antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
Immunogen Type
Peptide-KLH
Immunogen Description
Synthetic peptide corresponding to a region derived from 120-134 amino acids of human secretin receptor
Target Name
SCTR
Preparation and Storage
Store at -20 degree C/1 year

Testing Data

(Gel: 10%SDS-PAGE Lysate: 40 ug Human liver cancer tissue lysate Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds)

Testing Data (Gel: 10%SDS-PAGE Lysate: 40 ug Human liver cancer tissue lysate Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using 31290 (SCTR Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.)

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using 31290 (SCTR Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.)
Related Product Information for anti-SCTR antibody
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.
Product Categories/Family for anti-SCTR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,207 Da
NCBI Official Full Name
secretin receptor
NCBI Official Synonym Full Names
secretin receptor
NCBI Official Symbol
SCTR
NCBI Official Synonym Symbols
SR
NCBI Protein Information
secretin receptor
UniProt Protein Name
Secretin receptor
Protein Family
UniProt Gene Name
SCTR
UniProt Synonym Gene Names
SCT-R
UniProt Entry Name
SCTR_HUMAN

NCBI Description

The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008]

Uniprot Description

SCTR: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 2; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q14.1

Cellular Component: cytoplasmic microtubule; integral to plasma membrane; plasma membrane

Molecular Function: secretin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; digestion; excretion

Research Articles on SCTR

Similar Products

Product Notes

The SCTR sctr (Catalog #AAA9414139) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SCTR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SCTR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 Western blotting: 1:1000-1:5000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the SCTR sctr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCTR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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