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Testing Data (Gel: 8% SDS-PAGE Lysates (from left to right): A431 and K562 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)

Rabbit anti-Human GPR39 Polyclonal Antibody | anti-GPR39 antibody

GPR39 Antibody

Reactivity
Human
Applications
Western Blot
Purity
Antigen affinity purification.
Synonyms
GPR39; Polyclonal Antibody; GPR39 Antibody; G protein-coupled receptor 39; G-protein coupled receptor 39; MGC149541; anti-GPR39 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total GPR39 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
2.6 mg/ml (varies by lot)
Applicable Applications for anti-GPR39 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:200-1:1000
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human G protein-coupled receptor 39
Target Name
GPR39
Preparation and Storage
Store at -20°C.

Testing Data

(Gel: 8% SDS-PAGE Lysates (from left to right): A431 and K562 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)

Testing Data (Gel: 8% SDS-PAGE Lysates (from left to right): A431 and K562 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)
Related Product Information for anti-GPR39 antibody
G-protein coupled receptor 39 is a protein that in humans is encoded by the GPR39 gene. The predicted 453-amino acid GPR39 protein contains the 7 transmembrane domains characteristic of GPCRs. By sequence comparison with other GPCRs, the protein sequence of GPR39 is 27% and 32% identical to that of GSHR and neurotensin receptor-1, respectively. Northern blot analysis revealed that GPR39 is expressed widely as a 1.8- to 2-kb mRNA. A 3-kb transcript is present on Northern blots of some tissues, either in addition to the smaller mRNA or as the only hybridizing band.
Product Categories/Family for anti-GPR39 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
SDS-PAGE MW: 51kd
NCBI Official Full Name
G-protein coupled receptor 39
NCBI Official Synonym Full Names
G protein-coupled receptor 39
NCBI Official Symbol
GPR39
NCBI Protein Information
G-protein coupled receptor 39
UniProt Protein Name
G-protein coupled receptor 39
UniProt Gene Name
GPR39
UniProt Entry Name
GPR39_HUMAN

Uniprot Description

GPR39: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q21-q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; metal ion binding

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on GPR39

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Product Notes

The GPR39 gpr39 (Catalog #AAA9412829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPR39 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPR39 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:200-1:1000. Researchers should empirically determine the suitability of the GPR39 gpr39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPR39, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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