Rabbit GPR186 Polyclonal Antibody | anti-GPR186 antibody

GPR186 polyclonal antibody

Cat. Num. AAA3014876

• Gene Names: S100P; MIG9
• Reactivity: Human, Rat, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
• Synonyms: GPR186; Polyclonal Antibody; GPR186 polyclonal antibody; Protein S100-P; Migration-inducing gene 9 protein; MIG9; Protein S100-E; S100 calcium-binding protein P; S100P; S100E; anti-GPR186 antibody

• Host: Rabbit
• Reactivity: Human, Rat, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: S100-P polyclonal antibody detects endogenous levels of S100-P protein.
• Purity/Purification: The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-GPR186 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500~1000
• Immunogen: Synthetic peptide, corresponding to Human S100-P
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -25 degree C long term. Avoid freeze-thaw cycles.

Western Blot (WB)

(Western blot (WB) analysis of S100-P polyclonal antibody at 1:500 dilutionLaneA: MEF whole cell lysateLaneB: C6 whole cell lysateLaneC: A549 whole cell lysateLaneD: H1792 whole cell lysate)

Related Product Information for anti-GPR186 antibody

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.

NCBI and Uniprot Product Information

• NCBI GI #: 119602790
• NCBI GeneID: 6286
• UniProt Accession #: P25815; Q5J7W2
• Molecular Weight: 10,400 Da
• NCBI Official Full Name: S100 calcium binding protein P
• NCBI Official Synonym Full Names: S100 calcium binding protein P
• NCBI Official Symbol: S100P
• NCBI Official Synonym Symbols: MIG9
• NCBI Protein Information: protein S100-P; protein S100-E; S100 calcium-binding protein P; migration-inducing gene 9 protein
• UniProt Protein Name: Protein S100-P
• UniProt Gene Name: S100P
• UniProt Synonym Gene Names: S100E; MIG9
• UniProt Entry Name: S100P_HUMAN

NCBI Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

S100P: Homodimer. Interacts with S100PBP and S100Z. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Belongs to the S-100 family.

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: microvillus membrane; cytoplasm; nucleus

Molecular Function: protein binding; RAGE receptor binding; magnesium ion binding; calcium ion binding; calcium-dependent protein binding

Biological Process: response to organic substance; endothelial cell migration