Rabbit anti-Human, Mouse GPR179 Polyclonal Antibody | anti-GPR179 antibody

Anti-GPR179 Antibody

Cat. Num. AAA821872

• Gene Names: GPR179; CSNB1E; GPR158L; GPR158L1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: The antibody was purified by immunogen affinity chromatography.
• Synonyms: GPR179; Polyclonal Antibody; Anti-GPR179 Antibody; GPR158L; GPR158L1; Probable G-protein coupled receptor 179; Probable G-protein coupled receptor 158-like 1; GPR158-like; anti-GPR179 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of GPR179 protein.
• Purity/Purification: The antibody was purified by immunogen affinity chromatography.
• Form/Format: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Sequence Length: 2367

• Applicable Applications for anti-GPR179 antibody: Western Blot (WB)
• Application Notes: WB (1/500 - 1/1000)
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR179. The exact sequence is proprietary.
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of GPR179 expression in HeLa (A), SP2/0 (B) whole cell lysates.)

Related Product Information for anti-GPR179 antibody

Rabbit polyclonal antibody to GPR179

NCBI and Uniprot Product Information

• NCBI GI #: 629266054
• NCBI GeneID: 440435
• NCBI Accession #: NP_001004334.3
• NCBI GenBank Nucleotide #: NM_001004334.3
• UniProt Accession #: Q6PRD1
• Molecular Weight: 257,363 Da
• NCBI Official Full Name: probable G-protein coupled receptor 179
• NCBI Official Synonym Full Names: G protein-coupled receptor 179
• NCBI Official Symbol: GPR179
• NCBI Official Synonym Symbols: CSNB1E; GPR158L; GPR158L1
• NCBI Protein Information: probable G-protein coupled receptor 179; GPR158-like 1; probable G-protein coupled receptor 158-like 1
• UniProt Protein Name: Probable G-protein coupled receptor 179
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR179
• UniProt Synonym Gene Names: GPR158L; GPR158L1; GPR158-like
• UniProt Entry Name: GP179_HUMAN

NCBI Description

This gene encodes a member of the glutamate receptor subfamily of G protein-coupled receptors. The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. [provided by RefSeq, Apr 2012]

Uniprot Description

GPR179: Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells. Defects in GPR179 are the cause of congenital stationary night blindness type 1E (CSNB1E). An autosomal recessive, non-progressive retinal disorder characterized by impaired night vision, absence of the electroretinogram (ERG) b- wave, and variable degrees of involvement of other visual functions. Affected individuals have an ERG waveform that lacks the b-wave because of failure to transmit the photoreceptor signal through the retinal depolarizing bipolar cells. Belongs to the G-protein coupled receptor 3 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 3; Receptor, GPCR

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; visual perception

Disease: Night Blindness, Congenital Stationary, Type 1e