Rabbit GPR156 Polyclonal Antibody | anti-GPR156 antibody

GPR156 polyclonal antibody

Cat. Num. AAA3014846

• Gene Names: CLNS1A; CLCI; ICln; CLNS1B
• Reactivity: Human, Rat, Mouse
• Applications: Western Blot
• Purity: The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
• Synonyms: GPR156; Polyclonal Antibody; GPR156 polyclonal antibody; CLCI; CLNS1B; ICln; anti-GPR156 antibody

• Host: Rabbit
• Reactivity: Human, Rat, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: CLNS1A polyclonal antibody detects endogenous levels of CLNS1A protein.
• Purity/Purification: The protein was purified from E Coli and the purity is >95% (by SDS-PAGE)
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.4
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-GPR156 antibody: Western Blot (WB)
• Application Notes: WB: 1:500~1000
• Immunogen: Synthetic peptide, corresponding to Human CLNS1A
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Western Blot (WB)

(Western blot (WB) analysis of CLNS1A polyclonal antibody at 1:500 dilutionLaneA: H9C2 whole cell lysateLaneB: Aml-12 whole cell lysateLaneC: Jurkat whole cell lysateLaneD: HepG2 whole cell lysateLaneE: A549 whole cell lysate)

Related Product Information for anti-GPR156 antibody

This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 4502891
• NCBI GeneID: 1207
• NCBI Accession #: NP_001284.1
• NCBI GenBank Nucleotide #: NM_001293.2
• UniProt Accession #: P54105; Q0VDK6; Q9NRD2; Q9NRD3; B2RCS9
• Molecular Weight: 26,215 Da
• NCBI Official Full Name: methylosome subunit pICln
• NCBI Official Synonym Full Names: chloride channel, nucleotide-sensitive, 1A
• NCBI Official Symbol: CLNS1A
• NCBI Official Synonym Symbols: CLCI; ICln; CLNS1B
• NCBI Protein Information: methylosome subunit pICln; i(Cln); reticulocyte pICln; reticulocyte protein ICln; chloride channel regulatory protein; chloride ion current inducer protein; chloride channel, nucleotide sensitive 1A; chloride conductance regulatory protein ICln
• UniProt Protein Name: Methylosome subunit pICln
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: CLNS1A
• UniProt Synonym Gene Names: CLCI; ICLN; I(Cln); ClCI
• UniProt Entry Name: ICLN_HUMAN

NCBI Description

This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. [provided by RefSeq, Feb 2009]

Uniprot Description

ICLN: The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway. Belongs to the pICln (TC 1.A.47) family.

Protein type: Channel, chloride

Chromosomal Location of Human Ortholog: 11q13.5-q14

Cellular Component: nucleoplasm; cytoskeleton; cytoplasm; plasma membrane; cytosol; nucleus

Molecular Function: protein binding

Biological Process: spliceosomal snRNP biogenesis; gene expression; chloride transport; cell volume homeostasis