Rabbit anti-Human, Mouse GPR132 Polyclonal Antibody | anti-GPR132 antibody

GPR132 Antibody

Cat. Num. AAA9435036

• Gene Names: GPR132; G2A
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunocytochemistry
• Purity: Immunogen affinity purified
• Synonyms: GPR132; Polyclonal Antibody; GPR132 Antibody; G Protein Coupled Receptor G2A antibody; G2 accumulation protein antibody; G2A antibody; GP132_HUMAN antibody; GPR132 antibody; Probable G-protein coupled receptor 132 antibody; anti-GPR132 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Purity/Purification: Immunogen affinity purified
• Form/Format: 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• Applicable Applications for anti-GPR132 antibody: Western Blot (WB), Immunocytochemistry (ICC)
• Application Notes: WB: 1:500-1:1000; ICC: 1:100
• Immunogen: Peptide
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.

Western Blot (WB)

(Western blot analysis on 293 cell lysates using anti-GPR132 rabbit polyclonal antibodies.)

Immunofluorescence (IF)

(Immunofluorescent staining of A172 cells using anti- GPR132 rabbit polyclonal antibody.)

Related Product Information for anti-GPR132 antibody

Probable G-protein coupled receptor 132 is a protein that in humans is encoded by the GPR132 gene. It activates a G alpha protein, most likely G alpha (q). GPR132 may be involved in apoptosis and serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus.

Product Categories/Family for anti-GPR132 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 7019387
• NCBI GeneID: 29933
• NCBI Accession #: NP_037477.1
• NCBI GenBank Nucleotide #: NM_013345.2
• UniProt Accession #: Q9UNW8; Q9BSU2
• Molecular Weight: 42,499 Da
• NCBI Official Full Name: probable G-protein coupled receptor 132
• NCBI Official Synonym Full Names: G protein-coupled receptor 132
• NCBI Official Symbol: GPR132
• NCBI Official Synonym Symbols: G2A
• NCBI Protein Information: probable G-protein coupled receptor 132; G2 accumulation protein; G protein-coupled receptor G2A
• UniProt Protein Name: Probable G-protein coupled receptor 132
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR132
• UniProt Synonym Gene Names: G2A
• UniProt Entry Name: GP132_HUMAN

NCBI Description

This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression. [provided by RefSeq, Jul 2008]

Uniprot Description

GPR132: Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 14q32.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; G1/S transition of mitotic cell cycle