Rabbit GPR132 Polyclonal Antibody | anti-GPR132 antibody

GPR132 Antibody

Cat. Num. AAA7122026

• Gene Names: GPR132; G2A
• Reactivity: Human, Mouse, Monkey
• Applications: Western Blot, Immunofluorescence, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: GPR132; Polyclonal Antibody; GPR132 Antibody; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein; anti-GPR132 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Monkey
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Applicable Applications for anti-GPR132 antibody: Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IF: 1:200-1:1000; ELISA: 1:5000
• Immunogen: Synthesized peptide derived from the C-terminal region of human G2A.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of 293T cells using G2A Polyclonal Antibody)

Western Blot (WB)

(Western Blot analysis of various cells using G2A Polyclonal Antibody)

Product Categories/Family for anti-GPR132 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 7019387
• NCBI GeneID: 29933
• NCBI Accession #: NP_037477.1
• NCBI GenBank Nucleotide #: NM_013345.2
• UniProt Accession #: Q9UNW8; Q9BSU2
• Molecular Weight: 42,499 Da
• NCBI Official Full Name: probable G-protein coupled receptor 132
• NCBI Official Synonym Full Names: G protein-coupled receptor 132
• NCBI Official Symbol: GPR132
• NCBI Official Synonym Symbols: G2A
• NCBI Protein Information: probable G-protein coupled receptor 132; G2 accumulation protein; G protein-coupled receptor G2A
• UniProt Protein Name: Probable G-protein coupled receptor 132
• Protein Family: Probable G-protein coupled receptor
• UniProt Gene Name: GPR132
• UniProt Synonym Gene Names: G2A
• UniProt Entry Name: GP132_HUMAN

NCBI Description

This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression. [provided by RefSeq, Jul 2008]

Uniprot Description

GPR132: Receptor for an unknown ligand. Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 14q32.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; G1/S transition of mitotic cell cycle