Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue lysate, using Gnl3 Antibody (C-term). MBS9214653 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Rabbit anti-Mouse Gnl3 Polyclonal Antibody | anti-Gnl3 antibody
(Mouse) Gnl3 Antibody (C-term)
Gene Names
Gnl3; Ns
Reactivity
Mouse
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Gnl3; Polyclonal Antibody; (Mouse) Gnl3 Antibody (C-term); Guanine nucleotide-binding protein-like 3; Nucleolar GTP-binding protein 3; Nucleostemin; Ns; anti-Gnl3 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Gnl3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 450-483 amino acids from the C-terminal region of mouse Gnl3.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
505
Applicable Applications for anti-Gnl3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue lysate, using Gnl3 Antibody (C-term). MBS9214653 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue lysate, using Gnl3 Antibody (C-term). MBS9214653 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Related Product Information for anti-Gnl3 antibody
May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.
Product Categories/Family for anti-Gnl3 antibody
References
Tsai R.Y.L.,et al.Genes Dev. 16:2991-3003(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).
Meng L.,et al.Oncogene 30:1716-1726(2011).
Carninci P.,et al.Science 309:1559-1563(2005).
Trost M.,et al.Immunity 30:143-154(2009).
Meng L.,et al.Oncogene 30:1716-1726(2011).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60786
NCBI Official Full Name
guanine nucleotide-binding protein-like 3
NCBI Official Synonym Full Names
guanine nucleotide binding protein-like 3 (nucleolar)
NCBI Official Symbol
Gnl3
NCBI Official Synonym Symbols
Ns
NCBI Protein Information
guanine nucleotide-binding protein-like 3
UniProt Protein Name
Guanine nucleotide-binding protein-like 3
Protein Family
UniProt Gene Name
Gnl3
UniProt Synonym Gene Names
Ns
UniProt Entry Name
GNL3_MOUSE
Uniprot Description
GNL3: May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. May interact with p53/TP53 via its basic domain. Increased levels in lung tissue in cancer patients. Belongs to the MMR1/HSR1 GTP-binding protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Cell cycle regulation; Nucleolus; RNA-binding
Cellular Component: nucleoplasm; extracellular space; membrane; nucleolus; nucleus
Molecular Function: GTPase activity; protein binding; GTP binding; nucleotide binding
Biological Process: cell proliferation; ribosome biogenesis and assembly; regulation of cell proliferation
Research Articles on Gnl3
Similar Products
Product Notes
The Gnl3 gnl3 (Catalog #AAA9214653) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The (Mouse) Gnl3 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Gnl3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Gnl3 gnl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Gnl3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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