Rabbit anti-Human GNB5 Polyclonal Antibody | anti-GNB5 antibody

GNB5 Antibody

Cat. Num. AAA9413716

• Gene Names: GNB5; GB5
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: GNB5; Polyclonal Antibody; GNB5 Antibody; Guanine nucleotide-binding protein subunit beta-5; Transducin beta chain 5; Gbeta5; anti-GNB5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total GNB5 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 353

• Applicable Applications for anti-GNB5 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500~1:3000; Immunohistochemistry: 1:50~1:100
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human GNB5.
• Target Name: GNB5
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using GNB5 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using GNB5 antibody.)

Related Product Information for anti-GNB5 antibody

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.Poustka A., Genome Res. 11:422-435(2001).Aronstam R.S., Submitted (MAR-2002).The MGC Project Team, Genome Res. 14:2121-2127(2004).

Product Categories/Family for anti-GNB5 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 5729852
• NCBI GeneID: 10681
• NCBI Accession #: NP_006569.1
• NCBI GenBank Nucleotide #: NM_006578.3
• UniProt Accession #: O14775; Q9HAU9; Q9UFT3; B2RBR5
• Molecular Weight: 31,247 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit beta-5 isoform a
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), beta 5
• NCBI Official Symbol: GNB5
• NCBI Official Synonym Symbols: GB5
• NCBI Protein Information: guanine nucleotide-binding protein subunit beta-5
• UniProt Protein Name: Guanine nucleotide-binding protein subunit beta-5
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNB5
• UniProt Entry Name: GBB5_HUMAN

NCBI Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]

Uniprot Description

G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, heterotrimeric beta

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: plasma membrane; nucleus

Molecular Function: G-protein gamma-subunit binding; GTPase activity; protein binding; signal transducer activity; chaperone binding

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction