Rabbit anti-Human GNB4 Polyclonal Antibody | anti-GNB4 antibody

GNB4, ID (GNB4, Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4) (AP)

Cat. Num. AAA6303007

• Gene Names: GNB4; CMTD1F
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GNB4; Polyclonal Antibody; ID (GNB4; Guanine nucleotide-binding protein subunit beta-4; Transducin beta chain 4) (AP); Transducin beta chain 4; anti-GNB4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-GNB4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: GNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GNB4.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GNB4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GNB4 antibody detected the GNB4 protein (arrow).)

Related Product Information for anti-GNB4 antibody

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.

Product Categories/Family for anti-GNB4 antibody

Antibodies; G Proteins

References

Riemann, K., et al. Anticancer Res. 29(4):1271-1274(2009). Riemann, K., et al. Pharmacogenet. Genomics 18(11):999-1008(2008). Lamesch, P., et al. Genomics 89(3):307-315(2007). Rosskopf, D., et al. FEBS Lett. 544 (1-3), 27-32 (2003): Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003).

NCBI and Uniprot Product Information

• NCBI GI #: 11055998
• NCBI GeneID: 59345
• NCBI Accession #: NP_067642.1
• NCBI GenBank Nucleotide #: NM_021629.3
• UniProt Accession #: Q9HAV0; B3KMH5; D3DNR8
• Molecular Weight: 37,567 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit beta-4
• NCBI Official Synonym Full Names: G protein subunit beta 4
• NCBI Official Symbol: GNB4
• NCBI Official Synonym Symbols: CMTD1F
• NCBI Protein Information: guanine nucleotide-binding protein subunit beta-4
• UniProt Protein Name: Guanine nucleotide-binding protein subunit beta-4
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNB4

NCBI Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008]

Uniprot Description

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.