Western Blot
( Anti-GNB4 Antibody (Center) at 1:1000 dilution + human lung lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit GNB4 Polyclonal Antibody | anti-GNB4 antibody
GNB4 Antibody (Center)
Western Blot
( Anti-GNB4 Antibody (Center) at 1:1000 dilution + human lung lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot
( Anti-GNB4 Antibody (Center) at 1:1000 dilution + human lung lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(GNB4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GNB4 antibody detected the GNB4 protein (arrow).)
Western Blot (WB)
(GNB4 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the GNB4 antibody detected the GNB4 protein (arrow).)
proteins), which integrate signals between receptors and effector
proteins, are composed of an alpha, a beta, and a gamma subunit.
These subunits are encoded by families of related genes. This gene
encodes a beta subunit. Beta subunits are important regulators of
alpha subunits, as well as of certain signal transduction receptors
and effectors.
Riemann, K., et al. Pharmacogenet. Genomics 18(11):999-1008(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Rosskopf, D., et al. FEBS Lett. 544 (1-3), 27-32 (2003) :
Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003) :
NCBI and Uniprot Product Information
NCBI Description
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008]
Uniprot Description
G-beta 4: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family.
Protein type: G protein, heterotrimeric; G protein, heterotrimeric beta; Membrane protein, peripheral
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: lysosomal membrane; plasma membrane
Molecular Function: signal transducer activity; protein complex binding
Biological Process: substantia nigra development; energy reserve metabolic process; signal transduction
Disease: Charcot-marie-tooth Disease, Dominant Intermediate F
Research Articles on GNB4
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Product Notes
The GNB4 gnb4 (Catalog #AAA9212806) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 109-138. The GNB4 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Hamster, Zebrafish, Drosophila, Mouse, Rat, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's GNB4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GNB4 gnb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNB4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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