Western Blot (WB)
(Western blot analysis of GNAT2 expression in HepG2 (A) whole cell lysates.)
Rabbit anti-Human GNAT2 Polyclonal Antibody | anti-GNAT2 antibody
Anti-GNAT2 Antibody
Western Blot (WB)
(Western blot analysis of GNAT2 expression in HepG2 (A) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of GNAT2 expression in HepG2 (A) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008]
Uniprot Description
G-alpha t2: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4). Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein type: G protein; G protein, heterotrimeric alpha G((i/o/t/z)); G protein, heterotrimeric
Chromosomal Location of Human Ortholog: 1p13.1
Cellular Component: photoreceptor outer segment; photoreceptor inner segment; plasma membrane; heterotrimeric G-protein complex
Molecular Function: GTPase activity; GTP binding; G-protein-coupled receptor binding; metal ion binding; G-protein beta/gamma-subunit binding; G-protein coupled photoreceptor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; visual perception; retinal cone cell development; metabolic process; response to light intensity; phototransduction; detection of light stimulus involved in visual perception; detection of chemical stimulus involved in sensory perception of bitter taste
Disease: Achromatopsia 4
Research Articles on GNAT2
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Product Notes
The GNAT2 gnat2 (Catalog #AAA8306778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GNAT2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GNAT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GNAT2 gnat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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