Rabbit anti-Human GMFG Polyclonal Antibody | anti-GMFG antibody

GMFG, CT (GMFG, Glia maturation factor gamma) (MaxLight 490)

Cat. Num. AAA6302826

• Gene Names: GMFG; GMF-GAMMA
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
• Synonyms: GMFG; Polyclonal Antibody; CT (GMFG; Glia maturation factor gamma) (MaxLight 490); Glia maturation factor gamma; anti-GMFG antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human GMFG
• Purity/Purification: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

• Applicable Applications for anti-GMFG antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:50-100; Applications are based on unconjugated antibody.
• Immunogen: GMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109~138 amino acids from the C-terminal region of human GMFG.
• Conjugate: MaxLight490
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of GMFG Antibody (C-term) in CEM cell line lysates (35ug/lane). GMFG (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(GMFG Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GMFG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-GMFG antibody

Glia maturation factor gamma (GMFG) is a cytokine-responsive protein in erythropoietin-induced and granulocyte-colony stimulating factor-induced hematopoietic lineage development. It may be involved in glial differentiation, neural regeneration, and inhibition of tumor cell proliferation.

Product Categories/Family for anti-GMFG antibody

Antibodies; Proteins

References

Shi, Y., Genomics Proteomics Bioinformatics 4 (3), 145-155 (2006). Kawai, Y., Biochim. Biophys. Acta 1625 (3), 246-252 (2003). Peters, N., Neurogenetics 2 (3), 163-166 (1999).

NCBI and Uniprot Product Information

• NCBI GI #: 666335604
• NCBI GeneID: 9535
• NCBI Accession #: NP_001287937.1
• NCBI GenBank Nucleotide #: NM_001301008.1
• UniProt Accession #: O60234; Q6IB37
• Molecular Weight: 16,801 Da
• NCBI Official Full Name: glia maturation factor gamma isoform 2
• NCBI Official Synonym Full Names: glia maturation factor, gamma
• NCBI Official Symbol: GMFG
• NCBI Official Synonym Symbols: GMF-GAMMA
• NCBI Protein Information: glia maturation factor gamma
• UniProt Protein Name: Glia maturation factor gamma
• Protein Family: Glia maturation factor
• UniProt Gene Name: GMFG
• UniProt Synonym Gene Names: GMF-gamma
• UniProt Entry Name: GMFG_HUMAN

Uniprot Description

GMF-gamma: Belongs to the actin-binding proteins ADF family. GMF subfamily.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: intracellular

Molecular Function: growth factor activity; protein kinase inhibitor activity; enzyme activator activity; actin binding

Biological Process: positive regulation of catalytic activity; negative regulation of protein kinase activity; protein amino acid phosphorylation