Rabbit anti-Rat Glycine Transporter-1 Polyclonal Antibody | anti-slc6a9 antibody
Glycine Transporter-1 (GLYT1)
Gene Names
slc6a9; glyt1; glyt1b; slc6a9
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
Glycine Transporter-1; Polyclonal Antibody; Glycine Transporter-1 (GLYT1); Anti -Glycine Transporter-1 (GLYT1); anti-slc6a9 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat GLYT1. Species sequence homology: 100%- human GLYT1a, GLYT1b, GLY1c and 95% with mouse and bovine GLYT1.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid in 0.05% sodium azide.
Applicable Applications for anti-slc6a9 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-50,000 using 50-100ng G8168-03 Control peptide/well.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-50,000 using 50-100ng G8168-03 Control peptide/well.
Immunogen
Synthetic peptide corresponding to a 20aa sequence within the cytoplasmic, C-terminal domain of rat GLYT1 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-slc6a9 antibody
The glycine transporter belongs to a family of Na/Cl-dependent neurotransmitter transporters, predicted to contain as many as 12 transmembrane domains. Glycine receptor exists in 2 forms-GLYT1 and GLYT2. Form 1 has three other known isoforms (GLYT1a, GLYT1b, and GLYT1c) which may be produced by alternative spicing or promoter usage. Rodent Glyt1a and Glyt1b differ only by 10 amino acid at the N-terminus and expressed from the same gene. Although, the N-terminal part of mouse and rat GLYT1a is identical in mouse and rat, the N-terminus of GLYT1b are significantly different in these two species. The GLYT1c subtype has only been reported in humans. GLYT1a is expressed in CNS and peripheral organs. GLYT1b is localized in the CNS. Both neuron and Glial cells have GLYT1. More recent studies indicate that GLYt1b may not be brain specific. Immunolocalization studies on GLYT2 suggest that GLYT2 is responsible for terminating the neurotransmission at the strychnine synapses.
Product Categories/Family for anti-slc6a9 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
71,022 Da
NCBI Official Full Name
glycine transporter 1
NCBI Official Synonym Full Names
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
NCBI Official Symbol
slc6a9
NCBI Official Synonym Symbols
glyt1; glyt1b; slc6a9
NCBI Protein Information
sodium- and chloride-dependent glycine transporter 1; glyT-1; xGlyT1; solute carrier family 6 member 9
UniProt Protein Name
Sodium- and chloride-dependent glycine transporter 1
Protein Family
UniProt Gene Name
slc6a9
UniProt Synonym Gene Names
glyt1
UniProt Entry Name
SC6A9_XENLA
Uniprot Description
Function: Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission
By similarity. UniProtKB P48067
Subcellular location: Membrane; Multi-pass membrane protein
Potential.
Tissue specificity: First expressed in early tailbud stage embryos in the midbrain and anterior spinal cord, and weakly in the hindbrain. By late tailbud stages, expression extends posteriorly in the spinal cord to appear in between somites. Expressed in the forebrain, retina, between the somites and in the blood islands by the swimming tadpole stages. Ref.1
Sequence similarities: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily. [View classification]
Research Articles on slc6a9
Similar Products
Product Notes
The slc6a9 slc6a9 (Catalog #AAA612701) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glycine Transporter-1 (GLYT1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glycine Transporter-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000 ELISA: 1:10,000-50,000 using 50-100ng G8168-03 Control peptide/well. Researchers should empirically determine the suitability of the slc6a9 slc6a9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glycine Transporter-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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