Immunohistochemistry (IHC)
(IHC Analysis: Representative staining pattern on formalin-fixed, paraffin- embedded mouse spinal cord. Tissue was pretreated with citrate, pH 6.0 using antigen retrieval techniques. MBS621830 diluted to 1:100-500.)
Rabbit anti-Human Glycine Receptor alpha 3 subunit Polyclonal Antibody | anti-GLRA3 antibody
Glycine Receptor alpha 3 subunit (GLRA3, ligand gated ion channel, glycine receptor, alpha-3 polypeptide, glycine receptor, alpha 3)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Western Blot: 0.1ug/ml detected glycine receptor alpha 3 subunit on 10ug of fetal human brain tissue lysate.
Immunohistochemistry (Paraffin): 1:100-1:500 detected Glycine Receptor alpha 3 subunit in mouse spinal cord and mouse eye tissue.
Western Blot: 0.1ug/ml
Immunohistochemistry (IHC)
(IHC Analysis: Representative staining pattern on formalin-fixed, paraffin- embedded mouse spinal cord. Tissue was pretreated with citrate, pH 6.0 using antigen retrieval techniques. MBS621830 diluted to 1:100-500.)
Immunohistochemistry (IHC)
(IHC Analysis: Representative staining pattern on formalin-fixed, paraffin- embedded mouse spinal cord. Tissue was pretreated with citrate, pH 6.0 using antigen retrieval techniques. MBS621830 diluted to 1:100-500.)
Immunohistochemistry (IHC)
(IHC Analysis: Representative staining pattern on formalin-fixed, paraffin- embedded mouse eye. Tissue pretreated with citrate, pH 6.0 using antigen retrieval techniques. MBS621830 diluted to 1:100-1:300.)
Immunohistochemistry (IHC)
(IHC Analysis: Representative staining pattern on formalin-fixed, paraffin- embedded mouse eye. Tissue pretreated with citrate, pH 6.0 using antigen retrieval techniques. MBS621830 diluted to 1:100-1:300.)
Western Blot (WB)
(Western Blot Analysis: Fetal human brain lysate was resolved by electrophoresis, transferred to PVDF and probed with MBS621830. Proteins were visualized using IgG (HRP) Pab donkey x rabbit secondary antibody and a chemiluminescence detection system. Arrow indicates Glycine Receptor a3 subunit (48kD).)
Western Blot (WB)
(Western Blot Analysis: Fetal human brain lysate was resolved by electrophoresis, transferred to PVDF and probed with MBS621830. Proteins were visualized using IgG (HRP) Pab donkey x rabbit secondary antibody and a chemiluminescence detection system. Arrow indicates Glycine Receptor a3 subunit (48kD).)
NCBI and Uniprot Product Information
NCBI Description
The GLRA3 gene encodes the alpha-3 subunit of the neuronal glycine receptor, a ligand-gated chloride channel composed of ligand-binding alpha and structural beta polypeptides (Kingsmore et al., 1994 [PubMed 7894176]).[supplied by OMIM]
Uniprot Description
GLRA3: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub- subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter; Transporter, ion channel; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q34.1
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: transmitter-gated ion channel activity; extracellular-glycine-gated chloride channel activity; glycine binding
Biological Process: transmembrane transport
Research Articles on GLRA3
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Product Notes
The GLRA3 glra3 (Catalog #AAA621830) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glycine Receptor alpha 3 subunit (GLRA3, ligand gated ion channel, glycine receptor, alpha-3 polypeptide, glycine receptor, alpha 3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glycine Receptor alpha 3 subunit can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 0.1ug/ml detected glycine receptor alpha 3 subunit on 10ug of fetal human brain tissue lysate. Immunohistochemistry (Paraffin): 1:100-1:500 detected Glycine Receptor alpha 3 subunit in mouse spinal cord and mouse eye tissue. Western Blot: 0.1ug/ml. Researchers should empirically determine the suitability of the GLRA3 glra3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glycine Receptor alpha 3 subunit, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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