Rabbit anti-Mouse Glucagon-like Peptide 1 Receptor Polyclonal Antibody | anti-GLP1R antibody
Glucagon-like Peptide 1 Receptor (GLP1R)
Gene Names
GLP1R; MGC138331
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Glucagon-like Peptide 1 Receptor; Polyclonal Antibody; Glucagon-like Peptide 1 Receptor (GLP1R); Anti -Glucagon-like Peptide 1 Receptor (GLP1R); anti-GLP1R antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse GLP1R.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA.
Applicable Applications for anti-GLP1R antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 1:10,000-1:100,000. Using 50-100ng of control peptide/well.
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 1:10,000-1:100,000. Using 50-100ng of control peptide/well.
Immunogen
Synthetic peptide corresponding to 17aa near the mid region of mouse GLP1R conjugated to KLH. Species Sequence Homology: human and rat - 100%.
Species Sequence Homology
Human and rat - 100%.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-GLP1R antibody
Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C-terminal octapeptide. The glucagon precursor contains at least 3 intervening sequences that divide the protein-coding portion into 4 regions corresponding to the signal peptide and part of the N-terminal peptide, the remainder of the N-terminal peptide and glucagon, glucagon-like peptide-1 (GLP1), and GLP2. The GLP 1 & 2 stimulates intestinal growth and up regulates villus height in the small intestine, concomitant with increased crupt cell proliferation and decreased enterocyte apoptosis. The two GLP's are mainly produced in the A cells of the Islets of Langerhans in response to a drop in blood sugar concentration.
Product Categories/Family for anti-GLP1R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,026 Da
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 1 receptor
NCBI Official Symbol
GLP1R
NCBI Official Synonym Symbols
MGC138331
NCBI Protein Information
glucagon-like peptide 1 receptor; GLP-1R; GLP-1-R; GLP-1 receptor; OTTHUMP00000016340
UniProt Protein Name
Glucagon-like peptide 1 receptor
Protein Family
UniProt Gene Name
GLP1R
UniProt Entry Name
GLP1R_HUMAN
Uniprot Description
GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 2
Chromosomal Location of Human Ortholog: 6p21
Cellular Component: integral to membrane; plasma membrane
Molecular Function: transmembrane receptor activity; glucagon receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cAMP-mediated signaling; learning and/or memory; adenylate cyclase activation; energy reserve metabolic process; response to stress; regulation of insulin secretion; regulation of heart contraction
Research Articles on GLP1R
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Product Notes
The GLP1R glp1r (Catalog #AAA612873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glucagon-like Peptide 1 Receptor (GLP1R) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Glucagon-like Peptide 1 Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique. ELISA: 1:10,000-1:100,000. Using 50-100ng of control peptide/well. Researchers should empirically determine the suitability of the GLP1R glp1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucagon-like Peptide 1 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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