Human Sulfatase 2 (SULF2) ELISA Kit | SULF2 elisa kit

Human Sulfatase 2 (SULF2) ELISA Kit

Cat. Num. AAA451596

• Gene Names: SULF2; HSULF-2
• Reactivity: Human
• Synonyms: Sulfatase 2 (SULF2); Human Sulfatase 2 (SULF2) ELISA Kit; HSULF-2 Extracellular sulfatase S; SULF2 elisa kit

• Reactivity: Human
• Sequence Length: 870

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 1.56-100ng/mL
• Sensitivity: 0.56ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 240255483
• NCBI GeneID: 55959
• NCBI Accession #: NP_001155313.1
• NCBI GenBank Nucleotide #: NM_001161841.1
• UniProt Accession #: Q8IWU5; Q5JYE1; Q6UX86; Q96SG2; Q9H1H0; Q9UJR3; Q9ULH3; E1P5U6
• Molecular Weight: 100,156 Da
• NCBI Official Full Name: extracellular sulfatase Sulf-2 isoform a
• NCBI Official Synonym Full Names: sulfatase 2
• NCBI Official Symbol: SULF2
• NCBI Official Synonym Symbols: HSULF-2
• NCBI Protein Information: extracellular sulfatase Sulf-2
• UniProt Protein Name: Extracellular sulfatase Sulf-2
• Protein Family: Extracellular sulfatase
• UniProt Gene Name: SULF2
• UniProt Synonym Gene Names: KIAA1247; hSulf-2

NCBI Description

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]

Uniprot Description

Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.