Western Blot (WB)
(WB Suggested Anti-GGT2 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate)
Rabbit GGT2 Polyclonal Antibody | anti-GGT2 antibody
GGT2 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-GGT2 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate)
Western Blot (WB)
(WB Suggested Anti-GGT2 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate)
Target Description: GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).
NCBI and Uniprot Product Information
NCBI Description
GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
Uniprot Description
GGT2: Initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Belongs to the gamma-glutamyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.19.13; Membrane protein, integral; EC 2.3.2.2; Transferase
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: anchored to external side of plasma membrane; endoplasmic reticulum; perinuclear region of cytoplasm; plasma membrane
Molecular Function: gamma-glutamyltransferase activity
Biological Process: leukotriene biosynthetic process; glutathione metabolic process; xenobiotic metabolic process; glutathione biosynthetic process; zymogen activation
Research Articles on GGT2
Similar Products
Product Notes
The GGT2 ggt2 (Catalog #AAA3209374) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GGT2 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Pig, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's GGT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GGT2 ggt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LEIGRDTLRD GGSAVDAAIA ALLCVGLMNA HSMGIGVGLF LTIYNSTTGK. It is sometimes possible for the material contained within the vial of "GGT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
