Western Blot (WB)
(GGT6 polyclonal antibody. Western Blot analysis of GGT6 expression in human spleen.)
Mouse anti-Human GGT6 Polyclonal Antibody | anti-GGT6 antibody
GGT6 (Gamma-glutamyltransferase 6, Gamma-glutamyltranspeptidase 6, Glutathione Hydrolase 6, Gamma-glutamyltransferase 6 Heavy Chain, Gamma-glutamyltransferase 6 Light Chain, FLJ25990, FLJ90165)
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
GGT6; Polyclonal Antibody; GGT6 (Gamma-glutamyltransferase 6; Gamma-glutamyltranspeptidase 6; Glutathione Hydrolase 6; Gamma-glutamyltransferase 6 Heavy Chain; Gamma-glutamyltransferase 6 Light Chain; FLJ25990; FLJ90165); Anti -GGT6 (Gamma-glutamyltransferase 6; anti-GGT6 antibody
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human GGT6.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWVRVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSHGPGVYHHGAIISPAGRELLVAGGNVVDAGVGAALCLAVVHPHATGLGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFGRLPWPRLLVGPTTLAQEGFLVDTPLARALVARGTEGLCPLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAGDLGVEVPSAVPRPTLEPAEQLPVPQGILFTTPSPSAGPELLALLEAALRSGAPIPDPCPPFLQTAVSPESSALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKSTTSAWACPLILRGSLDDTEADVLGLVASGTPDVARAMTHTLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPFQGF
Applicable Applications for anti-GGT6 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human GGT6, aa1-493 (AAH63111).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(GGT6 polyclonal antibody. Western Blot analysis of GGT6 expression in human spleen.)
Western Blot (WB)
(GGT6 polyclonal antibody. Western Blot analysis of GGT6 expression in human spleen.)
Western Blot (WB)
(Western Blot analysis of GGT6 expression in transfected 293T cell line by GGT6 polyclonal antibody. Lane 1: GGT6 transfected lysate (54.23kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GGT6 expression in transfected 293T cell line by GGT6 polyclonal antibody. Lane 1: GGT6 transfected lysate (54.23kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-GGT6 antibody
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).
Product Categories/Family for anti-GGT6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
50,509 Da
NCBI Official Full Name
GGT6 protein
NCBI Official Synonym Full Names
gamma-glutamyltransferase 6
NCBI Official Symbol
GGT6
NCBI Protein Information
gamma-glutamyltransferase 6; GGT 6; glutathione hydrolase 6; gamma-glutamyltranspeptidase 6; gamma-glutamyltransferase 6 homolog
UniProt Protein Name
Gamma-glutamyltransferase 6
Protein Family
UniProt Gene Name
GGT6
UniProt Synonym Gene Names
GGT 6
UniProt Entry Name
GGT6_HUMAN
NCBI Description
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
Uniprot Description
Function: Cleaves glutathione conjugates
By similarity.
Catalytic activity: A (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid.Glutathione + H2O = L-cysteinylglycine + L-glutamate.
Pathway: Sulfur metabolism; glutathione metabolism.
Subunit structure: Heterodimer composed of the light and heavy chains. The active site is located in the light chain
By similarity.
Subcellular location: Membrane; Single-pass type II membrane protein
By similarity.
Sequence similarities: Belongs to the gamma-glutamyltransferase family.
Similar Products
Product Notes
The GGT6 ggt6 (Catalog #AAA645724) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GGT6 (Gamma-glutamyltransferase 6, Gamma-glutamyltranspeptidase 6, Glutathione Hydrolase 6, Gamma-glutamyltransferase 6 Heavy Chain, Gamma-glutamyltransferase 6 Light Chain, FLJ25990, FLJ90165) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GGT6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the GGT6 ggt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MERAEEPVVY QKLLPWEPSL ESEEEVEEEE TSEALVLNPR RHQDSSRNKA GGLPGTWVRV VAALLLLAVG CSLAVRQLQN QGRSTGSLGS VAPPPGGHSH GPGVYHHGAI ISPAGRELLV AGGNVVDAGV GAALCLAVVH PHATGLGAMF WGLFHDSSSG NSTALTSGPA QTLAPGLGLP AALPTLHLLH ARFGRLPWPR LLVGPTTLAQ EGFLVDTPLA RALVARGTEG LCPLLCHADG TPLGAGARAT NPQLAAVLRS AALAPTSDLA GDALLSLLAG DLGVEVPSAV PRPTLEPAEQ LPVPQGILFT TPSPSAGPEL LALLEAALRS GAPIPDPCPP FLQTAVSPES SALAAVDSSG SVLLLTSSLN CSFGSAHLSP STGVLLSNLV AKSTTSAWAC PLILRGSLDD TEADVLGLVA SGTPDVARAM THTLLRHLAA RPPTQAQHQH QGQQEPTEHP STCGQGTLLQ VAAHTEHAHV SSVPHACCPF QGF. It is sometimes possible for the material contained within the vial of "GGT6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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