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Immunohistochemistry (IHC) (Anti-CD79A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Mouse CD79A Monoclonal Antibody | anti-CD79A antibody

Mouse Monoclonal [clone HM57] (IgG1) to Human CD79A

Gene Names
CD79A; IGA; MB-1
Reactivity
Bovine, Chicken, Guinea pig, Horse, Human, Mouse, Opossum, Pig, Rabbit, Rat
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Protein A Purified
Synonyms
CD79A; Monoclonal Antibody; Mouse Monoclonal [clone HM57] (IgG1) to Human CD79A; Anti-CD79A Antibody (clone HM57) IHC-plus; CD79a antigen; Ig-alpha; MB-1; MB-1 membrane glycoprotein; Surface IgM-associated protein; MB1; Human CD79A; anti-CD79A antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Bovine, Chicken, Guinea pig, Horse, Human, Mouse, Opossum, Pig, Rabbit, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
HM57
Specificity
The antibody HM57 interacts with CD79a (Ig alpha), a 40-45 kD subunit of B cell antigen-specific receptor (BCR) and its early developmental forms. HLDA V; WS Code BC cB018. HLDA VI; WS Code BP 193. HLDA VI; WS Code BP 89. HLDA VI; WS Code B B103. HLDA VI; WS Code B CD79.4.
Purity/Purification
Protein A Purified
Form/Format
PBS, 15 mM sodium azide, pH 7.4
Concentration
1 mg/ml (varies by lot)
Sequence Length
226
Applicable Applications for anti-CD79A antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS)
Application Notes
Flo, IHC-Fr, IHC-P (15 ug/ml)
Usage: Flow Cytometry. Immunohistochemistry (paraffin sections). Recommended dilution:10 ug/ml. Immunohistochemistry (frozen sections).
Target Species
Human
Immunogen Description
Synthetic peptide corresponding to amino acids 202-216 of human CD79a.
Immunogen Type
Synthetic peptide - KLH conjugated
Immunogen
CD79A antibody was raised against synthetic peptide corresponding to amino acids 202-216 of human CD79a.
Preparation and Storage
+4 degree C, avoid freezing

Immunohistochemistry (IHC)

(Anti-CD79A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

Immunohistochemistry (IHC) (Anti-CD79A antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
973
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,786 Da
NCBI Official Full Name
B-cell antigen receptor complex-associated protein alpha chain isoform 1
NCBI Official Synonym Full Names
CD79a molecule, immunoglobulin-associated alpha
NCBI Official Symbol
CD79A
NCBI Official Synonym Symbols
IGA; MB-1
NCBI Protein Information
B-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; CD79a antigen (immunoglobulin-associated alpha); membrane-bound immunoglobulin-associated protein
UniProt Protein Name
B-cell antigen receptor complex-associated protein alpha chain
UniProt Gene Name
CD79A
UniProt Synonym Gene Names
IGA; MB1
UniProt Entry Name
CD79A_HUMAN

NCBI Description

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; external side of plasma membrane; lipid raft

Molecular Function: transmembrane receptor activity

Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation

Disease: Agammaglobulinemia 3, Autosomal Recessive

Research Articles on CD79A

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Product Notes

The CD79A cd79a (Catalog #AAA245778) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone HM57] (IgG1) to Human CD79A reacts with Bovine, Chicken, Guinea pig, Horse, Human, Mouse, Opossum, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD79A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS). Flo, IHC-Fr, IHC-P (15 ug/ml) Usage: Flow Cytometry. Immunohistochemistry (paraffin sections). Recommended dilution:10 ug/ml. Immunohistochemistry (frozen sections). Researchers should empirically determine the suitability of the CD79A cd79a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD79A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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