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Testing Data

Rabbit GFM2 Polyclonal Antibody | anti-GFM2 antibody

GFM2 Antibody

Gene Names
GFM2; EFG2; RRF2; MRRF2; hEFG2; MST027; RRF2mt; EF-G2mt; MSTP027; mEF-G 2
Reactivity
Human
Predicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
GFM2; Polyclonal Antibody; GFM2 Antibody; anti-GFM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
779
Applicable Applications for anti-GFM2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for anti-GFM2 antibody
Rabbit polyclonal GFM2 (1) antibody was raised against a recombinate human GFM2 protein 436-612 aa (BC015712).
References
(1) Callegari, S., Gregory, P.A., Sykes, M.J., et al. Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity. PLoS Genet. 8 (6), E1002755 (2012).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
57,060 Da
NCBI Official Full Name
GFM2 protein
NCBI Official Synonym Full Names
G elongation factor mitochondrial 2
NCBI Official Symbol
GFM2
NCBI Official Synonym Symbols
EFG2; RRF2; MRRF2; hEFG2; MST027; RRF2mt; EF-G2mt; MSTP027; mEF-G 2
NCBI Protein Information
ribosome-releasing factor 2, mitochondrial
UniProt Protein Name
Ribosome-releasing factor 2, mitochondrial
UniProt Gene Name
GFM2
UniProt Synonym Gene Names
hEFG2

NCBI Description

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.

Research Articles on GFM2

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Product Notes

The GFM2 gfm2 (Catalog #AAA8527181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GFM2 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GFM2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:200-1:1,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the GFM2 gfm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GFM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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