Western Blot (WB)
Rabbit GDF-15 Polyclonal Antibody | anti-GDF-15 antibody
Anti-GDF-15 Antibody
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Reactivity
Porcine, Monkey, Mouse, Human
Applications
Western Blot
Purity
Affinity purification
Synonyms
GDF-15; Polyclonal Antibody; Anti-GDF-15 Antibody; MIC1; PDF; PLAB; PTGFB; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor; anti-GDF-15 antibody
Host
Rabbit
Reactivity
Porcine, Monkey, Mouse, Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Affinity purified rabbit polyclonal antibody to detect GDF-15 expression in human, mouse, monkey and porcine samples
Purity/Purification
Affinity purification
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% NaCl; pH7.3; 30% glycerol; and 0.01% sodium azide
Applicable Applications for anti-GDF-15 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
WB data verified using HepG2 and NIH3T3 whole cell lysates
WB data verified using HepG2 and NIH3T3 whole cell lysates
Immunogen
KLH-conjugated synthetic peptide targeting a sequence within the center region of human GDF15.
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-GDF-15 antibody
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Product Categories/Family for anti-GDF-15 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,140 Da
NCBI Official Full Name
growth/differentiation factor 15
NCBI Official Synonym Full Names
growth differentiation factor 15
NCBI Official Symbol
GDF15
NCBI Official Synonym Symbols
PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
NCBI Protein Information
growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonster
UniProt Protein Name
Growth/differentiation factor 15
UniProt Gene Name
GDF15
UniProt Synonym Gene Names
MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1
UniProt Entry Name
GDF15_HUMAN
NCBI Description
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
Uniprot Description
GDF15: disulfide-linked. Belongs to the TGF-beta family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component: extracellular space; extracellular region
Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding
Biological Process: regulation of apoptosis; cell-cell signaling; transforming growth factor beta receptor signaling pathway; regulation of MAPKKK cascade; signal transduction; cell development
Research Articles on GDF-15
Similar Products
Product Notes
The GDF-15 gdf15 (Catalog #AAA847855) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GDF-15 Antibody reacts with Porcine, Monkey, Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDF-15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000 WB data verified using HepG2 and NIH3T3 whole cell lysates. Researchers should empirically determine the suitability of the GDF-15 gdf15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDF-15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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