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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using GDAP1 antibody.)

Rabbit GDAP1 Polyclonal Antibody | anti-GDAP1 antibody

GDAP1 antibody

Gene Names
GDAP1; CMT4; CMT4A; CMTRIA
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
GDAP1; Polyclonal Antibody; GDAP1 antibody; CMT4; CMT4A; CMTRIA; anti-GDAP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total GDAP1 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
290
Applicable Applications for anti-GDAP1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500 - 1:2000
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human GDAP1.
Target Name
GDAP1
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using GDAP1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using GDAP1 antibody.)
Related Product Information for anti-GDAP1 antibody
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.
Product Categories/Family for anti-GDAP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,480 Da
NCBI Official Full Name
ganglioside-induced differentiation-associated protein 1 isoform b
NCBI Official Synonym Full Names
ganglioside induced differentiation associated protein 1
NCBI Official Symbol
GDAP1
NCBI Official Synonym Symbols
CMT4; CMT4A; CMTRIA
NCBI Protein Information
ganglioside-induced differentiation-associated protein 1
UniProt Protein Name
Ganglioside-induced differentiation-associated protein 1
UniProt Gene Name
GDAP1
UniProt Synonym Gene Names
GDAP1
UniProt Entry Name
GDAP1_HUMAN

NCBI Description

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012]

Uniprot Description

GDAP1: the ganglioside-induced differentiation associated protein-1 gene causes autosomal recessive demyelinating or axonal Charcot-Marie-Tooth neuropathy (CMT).

Protein type: Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8q21.11

Cellular Component: mitochondrion; membrane; cytoplasm; nucleus; integral to mitochondrial outer membrane

Biological Process: mitochondrial fission; response to retinoic acid; protein targeting to mitochondrion

Disease: Charcot-marie-tooth Disease, Axonal, With Vocal Cord Paresis, Autosomal Recessive; Charcot-marie-tooth Disease, Axonal, Type 2k; Charcot-marie-tooth Disease, Type 4a; Charcot-marie-tooth Disease, Recessive Intermediate A

Research Articles on GDAP1

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Product Notes

The GDAP1 gdap1 (Catalog #AAA9404195) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GDAP1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GDAP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500 - 1:2000. Researchers should empirically determine the suitability of the GDAP1 gdap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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