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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded mouse pancreas using GCG Polyclonal Antibody at dilution of 1:300.)

Rabbit anti-Mouse, Rat GCG Polyclonal Antibody | anti-GCG antibody

GCG Polyclonal Antibody

Gene Names
Gcg; Glu; PPG; GLP-1
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence
Purity
Affinity Purification
Synonyms
GCG; Polyclonal Antibody; GCG Polyclonal Antibody; GLP 2; GLP1; GLP2; glucagon; GRPP; Glucagon like peptide 1; GRPP Oxyntomodulin; OXM; Proglucagon; anti-GCG antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
1 mg/mL (varies by lot)
Sequence Length
180
Applicable Applications for anti-GCG antibody
Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:500-1:1000
IF: 1:200-1:500
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse Glucagon
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded mouse pancreas using GCG Polyclonal Antibody at dilution of 1:300.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded mouse pancreas using GCG Polyclonal Antibody at dilution of 1:300.)

Immunofluorescence (IF)

(Immunofluorescence analysis of paraffin-embedded Rat pancreas using GCG Polyclonal Antibody at dilution of 1:200.Red is labeled with glucagon antibody and green is labeled with insulin antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of paraffin-embedded Rat pancreas using GCG Polyclonal Antibody at dilution of 1:200.Red is labeled with glucagon antibody and green is labeled with insulin antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of paraffin-embedded Mouse pancreas using GCG Polyclonal Antibody at dilution of 1:200.Red is labeled with glucagon antibody and green is labeled with insulin antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of paraffin-embedded Mouse pancreas using GCG Polyclonal Antibody at dilution of 1:200.Red is labeled with glucagon antibody and green is labeled with insulin antibody.)
Related Product Information for anti-GCG antibody
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Product Categories/Family for anti-GCG antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,906 Da
NCBI Official Full Name
glucagon preproprotein
NCBI Official Synonym Full Names
glucagon
NCBI Official Symbol
Gcg
NCBI Official Synonym Symbols
Glu; PPG; GLP-1
NCBI Protein Information
glucagon
UniProt Protein Name
Glucagon
Protein Family
UniProt Gene Name
Gcg
UniProt Synonym Gene Names
GRPP; OXM; OXY; GLP-1; GLP-1(7-37); GLP-1(7-36); GLP-2

NCBI Description

This gene encodes glucagon, a pancreatic hormone that counteracts the action of insulin in the bloodstream. The encoded protein is processed to generate glucagon and two other glucagon-like peptides, GLP1 and GLP2. Glucagon stimulates gluconeogenesis, glycogenolysis and lipolysis. GLP1 induces secretion of insulin, suppresses glucagon secretion and inhibits feeding. GLP2 induces intestinal absorption of glucose by stimulating the growth of intestinal cells and preventing apoptosis. [provided by RefSeq, Apr 2015]

Uniprot Description

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia ().

Research Articles on GCG

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Product Notes

The GCG gcg (Catalog #AAA2556335) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GCG Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GCG can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:500-1:1000 IF: 1:200-1:500. Researchers should empirically determine the suitability of the GCG gcg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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