Rabbit anti-Human GC Polyclonal Antibody | anti-GC antibody

GC (VDBP, DBP, VDB, Gc-globulin, Group-specific Component) (PE)

Cat. Num. AAA6379559

• Gene Names: GC; DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: GC; Polyclonal Antibody; GC (VDBP; DBP; VDB; Gc-globulin; Group-specific Component) (PE); anti-GC antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human GC.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-GC antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human GC, aa1-474 (AAH57228.1).
• Immunogen Sequence: MKRVLVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQEKTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMDKYTFELSRRTHLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKRSDFASNCCSINSPPLYCDSEIDAELKNIL
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(GC rabbit polyclonal antibody. Western Blot analysis of GC expression in human kidney.)

Western Blot (WB)

(Western Blot analysis of GC expression in transfected 293T cell line by GC polyclonal antibody. Lane 1: GC transfected lysate (52.9kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-GC antibody

Vitamin D binding protein (VDBP) is the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scaveging system. VDBP is a 52-58kD plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined.

Product Categories/Family for anti-GC antibody

Antibodies; Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 34785354
• NCBI GeneID: 2638
• Molecular Weight: 55,123 Da
• NCBI Official Full Name: Homo sapiens group-specific component (vitamin D binding protein), mRNA
• NCBI Official Synonym Full Names: GC, vitamin D binding protein
• NCBI Official Symbol: GC
• NCBI Official Synonym Symbols: DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51
• NCBI Protein Information: vitamin D-binding protein
• Protein Family: GCR1-dependent translation factor

NCBI Description

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]