Goat GBX2 Polyclonal Antibody | anti-GBX2 antibody

Goat Polyclonal to Human GBX2

Cat. Num. AAA246906

• Reactivity: Bat, Gibbon, Bovine, Chimpanzee, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat; Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: GBX2; Polyclonal Antibody; Goat Polyclonal to Human GBX2; Anti-GBX2 Antibody (Internal) IHC-plus; Gastrulation brain homeo box 2; Gastrulation brain homeobox 2; Homeobox protein GBX-2; Human GBX2; anti-GBX2 antibody

• Host: Goat
• Reactivity: Bat, Gibbon, Bovine, Chimpanzee, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat; Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human GBX2.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 348

• Applicable Applications for anti-GBX2 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA (1:16000), IHC-P (3.75 ug/ml), WB (0.1 - 0.3 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic peptide C-QGKDESKVEDDPK from an internal region of human GBX2 (NP_001476.2).
• Immunogen Type: Synthetic peptide
• Immunogen: GBX2 antibody was raised against synthetic peptide C-QGKDESKVEDDPK from an internal region of human GBX2 (NP_001476.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Pig (100%); Rabbit (92%).
• Antigen Modification: Internal
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-GBX2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC)

(Anti-GBX2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Western Blot (WB)

(Antibody (0.1 ug/ml) staining of Jurkat cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

• NCBI GI #: 45593144
• NCBI GeneID: 2637
• NCBI Accession #: NP_001476.2
• NCBI GenBank Nucleotide #: NM_001485.3
• UniProt Accession #: P52951; O43833; Q53RX5; Q9Y5Y1; B2RPH7
• Molecular Weight: 37,348 Da
• NCBI Official Full Name: homeobox protein GBX-2 isoform 1
• NCBI Official Synonym Full Names: gastrulation brain homeobox 2
• NCBI Official Symbol: GBX2
• NCBI Protein Information: homeobox protein GBX-2; gastrulation and brain-specific homeobox protein 2
• UniProt Protein Name: Homeobox protein GBX-2
• Protein Family: Homeobox protein
• UniProt Gene Name: GBX2
• UniProt Entry Name: GBX2_HUMAN

Uniprot Description

GBX2: May act as a transcription factor for cell pluripotency and differentiation in the embryo.

Protein type: DNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q37.2

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: axon guidance; midbrain-hindbrain boundary morphogenesis; nervous system development; autonomic nervous system development; inner ear morphogenesis; granule cell precursor proliferation; transcription, DNA-dependent; thalamus development; patterning of blood vessels; regulation of transcription, DNA-dependent; forebrain neuron development; rhombomere 2 development; cerebellum development; neural crest cell migration