Western Blot (WB)
(Western blotAll lanes: GBP5 antibody at 6ug/ml+ Mouse thymus tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 67,56 kDaObserved band size: 67 kDa)
Rabbit anti-Human, mouse GBP5 Polyclonal Antibody | anti-GBP5 antibody
GBP5 Antibody
Gene Names
GBP5; GBP-5
Reactivity
Human, mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
GBP5; Polyclonal Antibody; GBP5 Antibody; Guanylate-binding protein 5 (EC:3.6.5.-2 Publications; UNQ2427/PRO4987; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5; anti-GBP5 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
586
Applicable Applications for anti-GBP5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
Immunogen
Recombinant Human Guanylate-binding protein 5 protein (321-500AA)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160353 / sc-160354
Research Area
Immunology
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Western Blot (WB)
(Western blotAll lanes: GBP5 antibody at 6ug/ml+ Mouse thymus tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 67,56 kDaObserved band size: 67 kDa)
Western Blot (WB)
(Western blotAll lanes: GBP5 antibody at 6ug/ml+ Mouse thymus tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 67,56 kDaObserved band size: 67 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7002179 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7002179 at dilution of 1:100)
Related Product Information for anti-GBP5 antibody
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,247 Da
NCBI Official Full Name
guanylate-binding protein 5
NCBI Official Synonym Full Names
guanylate binding protein 5
NCBI Official Symbol
GBP5
NCBI Official Synonym Symbols
GBP-5
NCBI Protein Information
guanylate-binding protein 5
UniProt Protein Name
Guanylate-binding protein 5
Protein Family
UniProt Gene Name
GBP5
UniProt Synonym Gene Names
GBP-5
UniProt Entry Name
GBP5_HUMAN
Uniprot Description
GBP5: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Hydrolase
Chromosomal Location of Human Ortholog: 1p22.2
Cellular Component: cytoplasmic vesicle; Golgi membrane; membrane
Molecular Function: GTP binding; GTPase activity; identical protein binding; protein binding
Biological Process: inflammatory response; interleukin-1 beta secretion; metabolic process; positive regulation of innate immune response; protein homotetramerization
Research Articles on GBP5
Similar Products
Product Notes
The GBP5 gbp5 (Catalog #AAA7002179) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GBP5 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GBP5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the GBP5 gbp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GBP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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