Rabbit GBP5 Polyclonal Antibody | anti-GBP5 antibody

Anti-GBP5 Antibody (C-Terminus) IHC-plus

Cat. Num. AAA249564

• Gene Names: GBP5; GBP-5
• Reactivity: Mouse, Rat, Human
• Applications: Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
• Purity: Immunoaffinity purified
• Synonyms: GBP5; Polyclonal Antibody; Anti-GBP5 Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal (IgG) to Human GBP5; Human GBP5; GBP-TA antigen; GTP-binding protein 5; Guanylate binding protein 5; Guanylate-binding protein 5; GBP-5; anti-GBP5 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat, Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: GBP5 antibody is predicted to not cross-react with other GBP family members.
• Purity/Purification: Immunoaffinity purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 586

• Applicable Applications for anti-GBP5 antibody: Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
• Application Notes: IHC-P (10 ug/ml); WB (1 ug/ml)
• Immunogen: GBP5 antibody was raised against 16 amino acid peptide near the carboxy terminus of human GBP5.
• Immunogen Description: 16 amino acid peptide near the carboxy terminus of human GBP5.
• Antigen Modification: C-Terminus
• Target Species: Human
• Preparation and Storage: Long term: -20 degree C; Short term: 4 degree C; Avoid repeat freeze-thaw cycles

Immunohistochemistry (IHC)

(Immunohistochemistry of GBP5 in human liver tissue with GBP5 antibody at 2.5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-GBP5 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-GBP5 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunofluorescence (IF)

(Immunofluorescence of GBP5 in human liver tissue with GBP5 antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot analysis of GBP5 in rat liver tissue lysate with GBP5 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-GBP5 antibody

GBP5 Antibody, GBP-TA antigen Antibody, GTP-binding protein 5 Antibody, Guanylate binding protein 5 Antibody, Guanylate-binding protein 5 Antibody, GBP-5 Antibody Description: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge.

NCBI and Uniprot Product Information

• NCBI GI #: 37999757
• NCBI GeneID: 115362
• UniProt Accession #: Q96PP8; Q86TM5; B2RCE1
• Molecular Weight: 55,247 Da
• NCBI Official Full Name: Guanylate-binding protein 5
• NCBI Official Synonym Full Names: guanylate binding protein 5
• NCBI Official Symbol: GBP5
• NCBI Official Synonym Symbols: GBP-5
• NCBI Protein Information: guanylate-binding protein 5
• UniProt Protein Name: Guanylate-binding protein 5
• Protein Family: Guanylate-binding protein
• UniProt Gene Name: GBP5
• UniProt Synonym Gene Names: GBP-5
• UniProt Entry Name: GBP5_HUMAN

Uniprot Description

GBP5: Stimulates the NLRP3 inflammasome assembly upon bacterial challenge. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Hydrolase

Chromosomal Location of Human Ortholog: 1p22.2

Cellular Component: cytoplasmic vesicle; Golgi membrane; membrane

Molecular Function: GTP binding; GTPase activity; identical protein binding; protein binding

Biological Process: inflammatory response; interleukin-1 beta secretion; metabolic process; positive regulation of innate immune response; protein homotetramerization