Rabbit GBAS Polyclonal Antibody | anti-GBAS antibody

Rabbit Polyclonal to Human GBAS

Cat. Num. AAA247307

• Gene Names: GBAS; NIPSNAP2
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: GBAS; Polyclonal Antibody; Rabbit Polyclonal to Human GBAS; Anti-GBAS Antibody (Internal) IHC-plus; NIPSNAP2; Protein NipSnap homolog 2; Human GBAS; anti-GBAS antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS containing 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 286

• Applicable Applications for anti-GBAS antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
• Target Species: Human
• Immunogen Description: A 14 amino acid peptide near the center of human NIPSNAP2.
• Immunogen Type: Synthetic peptide
• Immunogen: GBAS antibody was raised against a 14 amino acid peptide near the center of human NIPSNAP2.
• Antigen Modification: Internal
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-GBAS antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of NIPSNAP2 in human skeletal muscle tissue lysate with NIPSNAP2 antibody at (A) 1 and (B) 2 ug/ml.)

Related Product Information for anti-GBAS antibody

Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor. The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.

NCBI and Uniprot Product Information

• NCBI GI #: 4503937
• NCBI GeneID: 2631
• NCBI Accession #: NP_001474.1
• NCBI GenBank Nucleotide #: NM_001483.2
• UniProt Accession #: O75323; O43801; Q53X96; C9IYJ3
• Molecular Weight: 29,053 Da
• NCBI Official Full Name: protein NipSnap homolog 2 isoform 1
• NCBI Official Synonym Full Names: glioblastoma amplified sequence
• NCBI Official Symbol: GBAS
• NCBI Official Synonym Symbols: NIPSNAP2
• NCBI Protein Information: protein NipSnap homolog 2; 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 2
• UniProt Protein Name: Protein NipSnap homolog 2
• Protein Family: Protein
• UniProt Gene Name: GBAS
• UniProt Synonym Gene Names: NIPSNAP2; NipSnap2
• UniProt Entry Name: NIPS2_HUMAN

NCBI Description

This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

GBAS: a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

Protein type: Autophagy; Cell surface

Chromosomal Location of Human Ortholog: 7p12

Cellular Component: membrane; mitochondrion; integral to plasma membrane

Molecular Function: protein binding

Biological Process: ATP biosynthetic process; oxidative phosphorylation