Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using GANAB Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human GANAB Polyclonal Antibody | anti-GANAB antibody
GANAB Antibody
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using GANAB Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using GANAB Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using GANAB Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using GANAB Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
Uniprot Description
GANAB: Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Belongs to the glycosyl hydrolase 31 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.2.1.84; Endoplasmic reticulum; Glycan Metabolism - N-glycan biosynthesis; Hydrolase
Chromosomal Location of Human Ortholog: 11q12.3
Cellular Component: endoplasmic reticulum lumen; extracellular matrix; membrane
Biological Process: protein folding
Disease: Polycystic Kidney Disease 3
Research Articles on GANAB
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Product Notes
The GANAB ganab (Catalog #AAA9417078) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GANAB Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GANAB can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the GANAB ganab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GANAB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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