Rabbit anti-Human, Mouse GALP Polyclonal Antibody | anti-GALP antibody
GALP Polyclonal Antibody
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
Western Blot (WB)
(Western blot analysis of Human fetal brain tissue and Mouse thymus tissue lysates using GALP Polyclonal Antibody at dilution of 1:500)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using GALP Polyclonal Antibody at dilution of 1:45(×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.[provided by RefSeq, Nov 2014]
Uniprot Description
GALP: Hypothalamic neuropeptide which binds to the G-protein- coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin- releasing hormone secretion. Isoform 2 exhibits potent and dose- dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Belongs to the galanin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.43
Cellular Component: extracellular region
Molecular Function: hormone activity
Biological Process: neuropeptide signaling pathway; behavioral response to starvation; regulation of appetite; defense response to bacterium; response to insulin stimulus
Research Articles on GALP
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Product Notes
The GALP galp (Catalog #AAA2559872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GALP Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GALP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the GALP galp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GALP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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