Rabbit GADD34 Polyclonal Antibody | anti-GADD34 antibody
GADD34 Antibody BIOTIN-Conjugated
Gene Names
Gadd34; CG3825; dGADD34; Dm-GADD34; DmelCG3825; dPPP1R15; gadd34; GADD34
Reactivity
Human, Mouse, RatPredicted: Bovine, Monkey
Applications
ELISA, Western Blot
Synonyms
GADD34; Polyclonal Antibody; GADD34 Antibody BIOTIN-Conjugated; Apoptosis associated protein; GADD 34; Growth arrest and DNA-damage-inducible 34; Myeloid differentiation primary response protein MyD116 homolog; PPP1R15A; Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody; anti-GADD34 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Bovine, Monkey
Predicted: Bovine, Monkey
Clonality
Polyclonal
Concentration
0.58 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
317
Applicable Applications for anti-GADD34 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:800-1:1,000
ELISA: 1:800-1:1,000
Western Blot: 1:500
ELISA: 1:800-1:1,000
Western Blot: 1:500
Immunogen
Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein.
Sequence: PATGVFLKSWVYQPGEDTEEE
Sequence: PATGVFLKSWVYQPGEDTEEE
Conjugation
BIOTIN. Ex: 493nm, Em: 528nm
Expression
induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells
Molecular Function
Apoptosis; Stress Response; Translation regulation
Structure
belongs to PPP1R15 family.
Subcellular Location
Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-GADD34 antibody
BIOTIN-Conjugated Growth arrest and DNA damage-inducible protein GADD34 Antibody
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Gadd34
NCBI Official Symbol
Gadd34
NCBI Official Synonym Symbols
CG3825; dGADD34; Dm-GADD34; DmelCG3825; dPPP1R15; gadd34; GADD34
NCBI Protein Information
CG3825 gene product from transcript CG3825-RA
Research Articles on GADD34
Similar Products
Product Notes
The GADD34 (Catalog #AAA541668) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GADD34 Antibody BIOTIN-Conjugated reacts with Human, Mouse, Rat Predicted: Bovine, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's GADD34 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:800-1:1,000 ELISA: 1:800-1:1,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the GADD34 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GADD34, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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