Testing Data
(Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE Primary antibody diluted at 1: 1000)
Rabbit anti-Human GADD 45 gamma Polyclonal Antibody | anti-GADD 45 gamma antibody
GADD 45 gamma antibody
Immunofluorescence: 1:100-1:200
Testing Data
(Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE Primary antibody diluted at 1: 1000)
Testing Data
(Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE Primary antibody diluted at 1: 1000)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed HeLa, using GADD45 gamma antibody at 1: 200 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed HeLa, using GADD45 gamma antibody at 1: 200 dilution.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
Uniprot Description
GADD45G: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. Belongs to the GADD45 family.
Protein type: Nuclear receptor co-regulator; Apoptosis; DNA repair, damage
Chromosomal Location of Human Ortholog: 9q22.1-q22.2
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: activation of MAPKK activity; positive regulation of apoptosis; regulation of cell cycle; apoptosis; multicellular organismal development; activation of MAPKKK activity; positive regulation of JNK cascade; negative regulation of protein kinase activity; response to stress; cell differentiation
Research Articles on GADD 45 gamma
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Product Notes
The GADD 45 gamma gadd45g (Catalog #AAA9404366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GADD 45 gamma antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GADD 45 gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the GADD 45 gamma gadd45g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GADD 45 gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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