Immunohistochemistry (IHC)
(Human Lung)
Rabbit GABPB2 Polyclonal Antibody | anti-GABPB1 antibody
GABPB2 antibody - C-terminal region
Immunohistochemistry (IHC)
(Human Lung)
Immunohistochemistry (IHC)
(Human Lung)
Immunohistochemistry (IHC)
(Human Spleen)
Immunohistochemistry (IHC)
(Human Spleen)
Western Blot (WB)
(Lanes:1. 40 ug human HK2 cell (kidney proximal tubular cell line) lysate2. 40 ug H2O2 treated human HK2 Cell lysate3. 40 ug H2O2 treated human HK2 Cell lysate4. 40 ug H2O2 treated human HK2 Cell lysate5. 40 ug H2O2 treated human HK2 Cell lysate6. 40 ug H2O2 treated human HK2 Cell lysatePrimary Antibody Dilution:1:1000Secondary Antibody:Goat anti-Rabbit HRPSecondary Antibody Dilution:1:2000Gene Name:GABPB2Submitted by:The University of Queensland, School of Medicine, Centre for Kidney Disease Research)
Western Blot (WB)
(Lanes:1. 40 ug human HK2 cell (kidney proximal tubular cell line) lysate2. 40 ug H2O2 treated human HK2 Cell lysate3. 40 ug H2O2 treated human HK2 Cell lysate4. 40 ug H2O2 treated human HK2 Cell lysate5. 40 ug H2O2 treated human HK2 Cell lysate6. 40 ug H2O2 treated human HK2 Cell lysatePrimary Antibody Dilution:1:1000Secondary Antibody:Goat anti-Rabbit HRPSecondary Antibody Dilution:1:2000Gene Name:GABPB2Submitted by:The University of Queensland, School of Medicine, Centre for Kidney Disease Research)
Western Blot (WB)
(WB Suggested Anti-GABPB2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysateGABPB1 is supported by BioGPS gene expression data to be expressed in HepG2)
Western Blot (WB)
(WB Suggested Anti-GABPB2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysateGABPB1 is supported by BioGPS gene expression data to be expressed in HepG2)
Target Description: GABPB2 is the GA-binding protein transcription factor, beta subunit. It forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 15q21.2
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter
Research Articles on GABPB1
Similar Products
Product Notes
The GABPB1 gabpb1 (Catalog #AAA3224672) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GABPB2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the GABPB1 gabpb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PDGQQVLTVP ATDIAEETVI SEEPPAKRQC IEIIENRVES AEIEEREALQ. It is sometimes possible for the material contained within the vial of "GABPB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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